Methacrylic Acid

Methacrylic Acid

SCHEMBL6678734

C=C(C)C(=O)O.C=C(C)C(=O)O.C=C(C)C(=O)O.C=C(C)C(=O)O.C=C(C)C(=O)O.C=C(C)C(=O)O.C=C(C)C(=O)OCC(COC(=O)C(=C)C)(COC(=O)C(=C)C)COC(=O)C(=C)C.OCC(CO)(CO)CO.OCC(CO)(CO)CO

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
ALDH1A1 P00352 3/20 0.40
MAPK1 P28482 2/20 0.40
HIF1A Q16665 2/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
THRB P10828 1/20 0.39
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL6846562 1.00 TSHR (0.41) TSHRALDH1A1MAPK1HIF1ATP53
Methacrylic Acid SCHEMBL1463859 0.96 TSHR (0.41) TSHRALDH1A1MAPK1HIF1ATP53
Methacrylic Acid SCHEMBL11166297 0.96 TSHR (0.41) TSHRALDH1A1MAPK1HIF1ATP53
Methacrylic Acid SCHEMBL5799367 0.96 TSHR (0.41) TSHRALDH1A1MAPK1HIF1ATP53
Methacrylic Acid SCHEMBL4075755 0.96 TSHR (0.41) TSHRALDH1A1MAPK1HIF1ATP53
Methacrylic Acid SCHEMBL4614167 0.96 TSHR (0.41) TSHRALDH1A1MAPK1HIF1ATP53
Methacrylic Acid SCHEMBL1091866 0.93 TSHR (0.39) TSHRALDH1A1MAPK1HIF1ATP53
Methacrylic Acid SCHEMBL3685193 0.92 ALDH1A1 (0.39) TSHRALDH1A1MAPK1HIF1ATP53
Methacrylic Acid SCHEMBL10790154 0.91 THRB (0.40) TSHRALDH1A1MAPK1HIF1ATP53
SCHEMBL23498428 0.90 ALDH1A1 (0.48) TSHRALDH1A1MAPK1HIF1ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004046803-A1 LIQUID CRYSTAL DEVICES WITH REDUCED SURFACE ANCHORING ENERGY QINETIQ LIMITED (GB) 2004-06-03 WO disclosed
EP-1046078-A1 LIQUID CRYSTAL DEVICE ALIGNMENT Hewlett-Packard Company (US) 2000-10-25 EP disclosed
WO-1999018474-A1 LIQUID CRYSTAL DEVICE ALIGNMENT HEWLETT-PACKARD COMPANY (US) 1999-04-15 WO disclosed