SCHEMBL212921

SCHEMBL212921

Cc1c(O)cc(Cl)c(Cl)c1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 10/20 0.55
TSHR P16473 9/20 0.55
HPGD P15428 7/20 0.55
CASP1 P29466 1/20 0.55
CYP3A4 P08684 7/20 0.50
HSP90AA1 P07900 2/20 0.50
MAPK1 P28482 2/20 0.44
ALDH1A1 P00352 4/20 0.42
ACHE P22303 2/20 0.42
CRHBP P24387 1/20 0.42
CRHR2 Q13324 1/20 0.42
SIRT1 Q96EB6 1/20 0.39
ALOX15 P16050 3/20 0.39
MAPT P10636 2/20 0.39
ALOX12 P18054 2/20 0.39
GAA P10253 1/20 0.39
CHRM1 P11229 2/20 0.39
TBXA2R P21731 2/20 0.39
ADRA1A P35348 2/20 0.39
HTR2B P41595 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11384008 0.82 HSD17B10 (0.52) HSD17B10TSHRHPGDCASP1CYP3A4
SCHEMBL22138546 0.82 HSD17B10 (0.59) HSD17B10TSHRHPGDCASP1CYP3A4
SCHEMBL10769365 0.82 HSD17B10 (0.65) HSD17B10TSHRHPGDCASP1CYP3A4
SCHEMBL22454878 0.82 HSD17B10 (0.43) HSD17B10TSHRHPGDCASP1CYP3A4
SCHEMBL1882971 0.80 HSD17B10 (0.55) HSD17B10TSHRHPGDCASP1CYP3A4
SCHEMBL6722124 0.80 MAPT (0.54) HSD17B10TSHRHPGDCASP1CYP3A4
SCHEMBL2659253 0.80 HSD17B10 (0.50) HSD17B10TSHRHPGDCASP1CYP3A4
SCHEMBL6678885 0.77 HSD17B10 (0.43) HSD17B10TSHRHPGDCASP1CYP3A4
SCHEMBL11055543 0.77 HSD17B10 (0.46) HSD17B10TSHRHPGDCASP1CYP3A4
SCHEMBL10592132 0.77 HSD17B10 (0.59) HSD17B10TSHRHPGDCASP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 820 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4608363-A1 A COMPOSITION FOR IMPROVING EFFECTIVENESS OF DYE PRECURSORS FOR CHANGE OF COLOUR OF HAIR Cavinkare Pvt. Ltd (IN) 2025-09-03 EP claimed
WO-2024089704-A1 A COMPOSITION FOR IMPROVING EFFECTIVENESS OF DYE PRECURSORS FOR CHANGE OF COLOUR OF HAIR CAVINKARE PVT.LTD. (IN) 2024-05-02 WO claimed
EP-1494995-B1 3-AMINOPHENOL DERIVATIVES SUBSTITUTED IN THE 2-POSITION, AND DYES CONTAINING THESE COMPOUNDS PROCTER & GAMBLE (US) 2010-09-22 EP claimed
US-RE41549-E1 Dyes for keratin fibers, the dyes containing n-benzyl-p-phenylenediamine derivatives and novel n-benzyl-p-phenylenediamine derivatives WELLA AG (DE) 2010-08-24 US claimed
EP-1670423-B1 DYE-CONTAINING PELLETS FOR DYEING KERATIN FIBRES WELLA AG (DE) 2008-10-08 EP claimed
EP-1601335-B1 MEANS AND METHOD FOR THE SIMULTANEOUS BLEACHING AND DYEING OF KERATIN FIBRES WELLA AG (DE) 2008-03-19 EP claimed
US-7326254-B2 Means and method for the simultaneous bleaching and dyeing of keratin fibres WELLA AG (DE) 2008-02-05 US claimed
EP-1351945-B1 NOVEL 1,4-DIAMINO-2-(THIAZOL-2-YL)BENZENE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS WELLA AG (DE) 2008-01-23 EP claimed
EP-1599178-B1 MEANS AND METHOD FOR DYEING KERATIN FIBRES WELLA AG (DE) 2007-12-19 EP claimed
US-7294151-B2 Means and method for dyeing keratin fibres WELLA AG (DE) 2007-11-13 US claimed
US-6436152-B1 Substituted 2-aminoalky-1,4-diaminobenzene compounds and oxidation dye precursor compositions containing same WELLA AKTIENGESELLSCHAFT (DE) 2002-08-20 US claimed
EP-0963982-B1 New diaminobenzene derivatives and these componends containing colouring agents WELLA AG (DE) 2002-03-13 EP claimed
US-20010054207-A1 p-aminophenol derivative compounds and dye compositions containing same WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) 2001-12-27 US claimed
EP-0943614-B1 Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives WELLA AG (DE) 2001-12-12 EP claimed
EP-1153917-A1 p-Aminophenol derivatives and colorants containing them Wella Aktiengesellschaft (DE) 2001-11-14 EP claimed
EP-1116711-A2 2-aminoalkyl-1,4-diaminobenzene derivatives and dye composition containing these compounds Wella Aktiengesellschaft (DE) 2001-07-18 EP claimed
US-6042620-A FOR DYEING KERATIN FIBERS SUCH AS HAIR WELLA AG (DE) 2000-03-28 US claimed
EP-0963982-A2 New diaminobenzene derivatives and these componends containing colouring agents Wella Aktiengesellschaft (DE) 1999-12-15 EP claimed
EP-0943614-A2 Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives Wella Aktiengesellschaft (DE) 1999-09-22 EP claimed
US-4904275-A OXIDIZER L'OREAL (FR) 1990-02-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010054207-A1 p-aminophenol derivative compounds and dye compositions containing same KRT18, AASDHPPT, S100P HSD17B10 702/4885TSHR 4685/4885HPGD 500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.