Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.52 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.52 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.52 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.52 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.52 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.52 |
| ▸ | PTGIR | P43119 | 2/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6681875 | 0.99 | SIGMAR1 (0.51) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6675007 | 0.76 | GRIN2D (0.49) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6677094 | 0.76 | SIGMAR1 (0.55) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL23510480 | 0.76 | PTGIR (0.57) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1797934 | 0.76 | PTGIR (0.57) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL6679173 | 0.75 | SIGMAR1 (0.48) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL6675353 | 0.75 | SIGMAR1 (0.56) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4368824 | 0.74 | MEN1 (0.59) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6674697 | 0.73 | SIGMAR1 (0.57) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6676046 | 0.73 | ALDH1A1 (0.47) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | claimed |