Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 3/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | GRK6 | P43250 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6677311 | 0.91 | FGFR1 (0.40) | SLC2A1RXFP1FGFR1KDM4EADRA2A | |
| SCHEMBL6674890 | 0.86 | NCF1 (0.41) | SLC2A1ELANEKCNH2 | |
| Hydrochloric Acid SCHEMBL6676590 | 0.82 | BCHE (0.37) | SLC2A1NPY1RNPY5RAPPBCHE | |
| SCHEMBL3383053 | 0.82 | METAP2 (0.32) | KDM4E | |
| SCHEMBL6677689 | 0.78 | KCNH2 (0.35) | NPY1RNPY5RKDM4EKCNH2CA1 | |
| SCHEMBL6675559 | 0.75 | GRK6 (0.35) | NPY1RNPY5RKDM4EAURKAGRK6 | |
| SCHEMBL6679519 | 0.75 | KDM4E (0.40) | KDM4EGRK6 | |
| SCHEMBL6674578 | 0.74 | SRC (0.43) | ACHEKDM4EADRA2AADRA2BADRA2C | |
| SCHEMBL3384903 | 0.74 | METAP2 (0.36) | BCHEACHERXFP1KDM4EKCNH2 | |
| SCHEMBL3385028 | 0.73 | CA12 (0.34) | CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1468688-A2 | Benzoazine mono-N-oxides and benzoazine 1,4 dioxides and compositions therefrom for the therapeutic use in cancer treatments | Auckland Uniservices Limited (NZ) | 2004-10-20 | — | — | EP | disclosed |