Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.48 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.48 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6683498 | 0.89 | MEN1 (0.59) | MEN1KMT2AMAPTTSHRADORA3 | |
| SCHEMBL6677449 | 0.88 | MEN1 (0.59) | MEN1KMT2AMAPTTSHRADORA3 | |
| SCHEMBL6683268 | 0.83 | MAPT (0.62) | MEN1KMT2AMAPTTSHRADORA3 | |
| SCHEMBL6681967 | 0.81 | MEN1 (0.66) | MEN1KMT2AMAPTTSHRADORA3 | |
| SCHEMBL6677471 | 0.80 | ALDH1A1 (0.72) | MEN1KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL6676240 | 0.79 | MEN1 (0.62) | MEN1KMT2AMAPTTSHRADORA3 | |
| SCHEMBL6681190 | 0.79 | MEN1 (0.64) | MEN1KMT2AMAPTTSHRADORA3 | |
| SCHEMBL6672985 | 0.79 | MEN1 (0.59) | MEN1KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL6684407 | 0.77 | KDM4E (0.70) | MEN1KMT2AMAPTTSHRADORA3 | |
| SCHEMBL6678084 | 0.75 | MAPT (0.72) | MEN1KMT2AMAPTTSHRADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | disclosed |