Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.66 |
| ▸ | MAPT | P10636 | 7/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | XBP1 | P17861 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6683498 | 0.82 | MEN1 (0.59) | MEN1KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL6679150 | 0.81 | MEN1 (0.59) | MEN1KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL6677449 | 0.81 | MEN1 (0.59) | MEN1KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL6681190 | 0.81 | MEN1 (0.64) | MEN1KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL6672985 | 0.81 | MEN1 (0.59) | MEN1KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL6678084 | 0.80 | MAPT (0.72) | MEN1KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL6686801 | 0.79 | MEN1 (0.71) | MEN1KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL6676240 | 0.78 | MEN1 (0.62) | MEN1KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL6677433 | 0.77 | ALDH1A1 (0.70) | MEN1KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL6677445 | 0.76 | MEN1 (0.58) | MEN1KMT2AMAPTTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | claimed |
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | disclosed |