Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | CDK7 | P50613 | 1/20 | 0.36 |
| ▸ | CCNH | P51946 | 1/20 | 0.36 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.36 |
| ▸ | IDH2 | P48735 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.34 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6677683 | 0.89 | KCNH2 (0.36) | KCNH2SYKKDM1AEHMT2RCOR1 | |
| SCHEMBL2776366 | 0.84 | SCN9A (0.42) | KDM1AEHMT2RCOR1NCF1SCN9A | |
| SCHEMBL2774178 | 0.83 | KCNH2 (0.40) | KCNH2KDM1AEHMT2RCOR1NCF1 | |
| SCHEMBL6679102 | 0.80 | FLT3 (0.39) | KCNH2KDM1AEHMT2RCOR1NCF1 | |
| SCHEMBL2776640 | 0.80 | KDM1A (0.42) | KMT2AKDM1AEHMT2RCOR1SCN9A | |
| SCHEMBL6673922 | 0.79 | DNM2 (0.37) | KCNH2KDM1AEHMT2RCOR1NCF1 | |
| SCHEMBL6678946 | 0.78 | NCF1 (0.44) | KMT2AKDM1AEHMT2RCOR1NCF1 | |
| SCHEMBL2776163 | 0.78 | POLB (0.41) | SCN9ARAD52 | |
| SCHEMBL6678638 | 0.78 | KCNH2 (0.38) | KCNH2MEN1KMT2A | |
| SCHEMBL6673992 | 0.77 | HTR1D (0.35) | KCNH2NPY1RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1468688-A2 | Benzoazine mono-N-oxides and benzoazine 1,4 dioxides and compositions therefrom for the therapeutic use in cancer treatments | Auckland Uniservices Limited (NZ) | 2004-10-20 | — | — | EP | disclosed |