Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.74 |
| ▸ | MAPT | P10636 | 4/20 | 0.74 |
| ▸ | HTT | P42858 | 4/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.74 |
| ▸ | MEN1 | O00255 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.69 |
| ▸ | GSK3A | P49840 | 1/20 | 0.63 |
| ▸ | GSK3B | P49841 | 1/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18742319 | 1.00 | ALDH1A1 (0.74) | ALDH1A1MAPTHTTKDM4EMEN1 | |
| SCHEMBL6689637 | 0.90 | ALDH1A1 (0.65) | ALDH1A1MAPTHTTKDM4EMEN1 | |
| SCHEMBL6687187 | 0.90 | ALDH1A1 (0.67) | ALDH1A1MAPTHTTKDM4EMEN1 | |
| SCHEMBL28551638 | 0.90 | MEN1 (0.79) | ALDH1A1MAPTHTTKDM4EMEN1 | |
| SCHEMBL30173920 | 0.90 | MEN1 (0.79) | ALDH1A1MAPTHTTKDM4EMEN1 | |
| SCHEMBL28546977 | 0.90 | MEN1 (0.79) | ALDH1A1MAPTHTTKDM4EMEN1 | |
| SCHEMBL30173806 | 0.90 | MEN1 (0.79) | ALDH1A1MAPTHTTKDM4EMEN1 | |
| SCHEMBL6683010 | 0.88 | MAPT (0.62) | ALDH1A1MAPTHTTKDM4EMEN1 | |
| SCHEMBL6678048 | 0.88 | ALDH1A1 (0.62) | ALDH1A1MAPTHTTKDM4EMEN1 | |
| SCHEMBL28549042 | 0.87 | ALDH1A1 (0.72) | ALDH1A1MAPTHTTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | claimed |
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | disclosed |