SCHEMBL6679495

SCHEMBL6679495

O=C(O)c1c(CCc2ccccc2)ccc2c1Cc1ccccc1O2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 2/20 0.44
PTGS2 P35354 2/20 0.44
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
BID P55957 1/20 0.39
BCL2L1 Q07817 1/20 0.39
MCL1 Q07820 1/20 0.39
BAK1 Q16611 1/20 0.39
HDAC1 Q13547 3/20 0.38
HDAC2 Q92769 3/20 0.38
HDAC8 Q9BY41 3/20 0.38
HDAC6 Q9UBN7 3/20 0.38
HDAC3 O15379 2/20 0.38
HDAC5 Q9UQL6 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
MAPK1 P28482 1/20 0.38
ADRA1A P35348 1/20 0.38
HDAC4 P56524 1/20 0.38
SLC6A3 Q01959 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11850413 0.92 BID (0.46) MAOAMAOBBIDBCL2L1MCL1
SCHEMBL4705461 0.88 MAOA (0.43) PTGS1PTGS2MAOAMAOBTDP1
SCHEMBL2804823 0.86 MAOA (0.42) PTGS1PTGS2MAOAMAOBBID
SCHEMBL2313646 0.85 MAOA (0.46) PTGS1PTGS2MAOAMAOBTDP1
SCHEMBL4743622 0.84 PTGER2 (0.41) MAOAMAOBBIDBCL2L1MCL1
SCHEMBL4747073 0.84 MAOA (0.40) MAOAMAOBBIDBCL2L1MCL1
SCHEMBL135629 0.84 BID (0.43) MAOAMAOBBIDBCL2L1MCL1
SCHEMBL16563060 0.83 MAOA (0.44) PTGS1PTGS2MAOAMAOBTDP1
Potassium SCHEMBL4602990 0.83 MAOA (0.44) PTGS1PTGS2MAOAMAOBTDP1
SCHEMBL2421075 0.83 MAOA (0.39) PTGS1PTGS2MAOAMAOBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1373238-B1 ALKYLXANTHATES AND THEIR USE AS PESTICIDES COUNCIL SCIENT IND RES (IN) 2004-11-03 EP disclosed
US-6583175-B2 Used as insect growth regulatory for pest management in agricultural fields no or less environmental impact COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2003-06-24 US disclosed