Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | FER | P16591 | 1/20 | 0.35 |
| ▸ | LTK | P29376 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11775513 | 0.71 | NPC1 (0.34) | MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL181833 | 0.65 | MEN1 (0.35) | MAOAMAOBIDO1GSK3BLMNA | |
| SCHEMBL68595 | 0.64 | CA12 (0.45) | LRRK2MAOAMAOBPDGFRAFER | |
| SCHEMBL21311994 | 0.64 | LRRK2 (0.58) | LRRK2MAOAMAOBPDGFRAFER | |
| Hydrochloric Acid SCHEMBL2034214 | 0.63 | CA12 (0.43) | LRRK2MAOAMAOBPDGFRAFER | |
| Hydrochloric Acid SCHEMBL10863156 | 0.63 | CA12 (0.43) | LRRK2MAOAMAOBPDGFRAFER | |
| Hydrochloric Acid SCHEMBL7397522 | 0.61 | CA12 (0.42) | LRRK2MAOAMAOBPDGFRAFER | |
| SCHEMBL2000139 | 0.61 | MAOA (0.39) | LRRK2MAOAMAOBPDGFRAFER | |
| SCHEMBL1050699 | 0.61 | AHR (0.57) | LRRK2MAOAMAOBPDGFRAFER | |
| SCHEMBL68581 | 0.61 | MEN1 (0.61) | LRRK2MAOAMAOBPDGFRAFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014388-A1 | 6,6-FUSED HETEROARYL DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |