Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | GLA | P06280 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.55 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | NCF1 | P14598 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 4/20 | 0.42 |
| ▸ | HTR3A | P46098 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9415823 | 0.85 | KDM4E (0.58) | ALDH1A1HPGDPOLBKDM4EGLA | |
| SCHEMBL5592991 | 0.81 | KMT2A (0.59) | ALDH1A1HPGDPOLBKDM4EGLA | |
| SCHEMBL27791326 | 0.81 | KMT2A (0.55) | ALDH1A1HPGDPOLBKDM4EGLA | |
| SCHEMBL22067807 | 0.80 | ALDH1A1 (0.46) | ALDH1A1HPGDPOLBKDM4EGLA | |
| SCHEMBL4939236 | 0.80 | ALDH1A1 (0.61) | ALDH1A1HPGDPOLBKDM4EGLA | |
| SCHEMBL27517531 | 0.80 | SLC2A1 (0.59) | ALDH1A1HPGDPOLBKDM4EGLA | |
| Hydrochloric Acid SCHEMBL15673453 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HPGDPOLBKDM4EGLA | |
| SCHEMBL6249834 | 0.78 | TLR8 (0.52) | ALDH1A1HPGDPOLBKDM4EGLA | |
| SCHEMBL30255070 | 0.78 | ALDH1A1 (0.50) | ALDH1A1HPGDPOLBKDM4EGLA | |
| SCHEMBL27860753 | 0.77 | KMT2A (0.50) | ALDH1A1HPGDPOLBKDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111909173-B | Benzoxazepine oxazolidinone compounds and methods of use thereof | 豪夫迈·罗氏有限公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-119497575-A | Cryopreservation of NK cell products for spot immunotherapy | 得克萨斯大学体系董事会 | 2025-02-21 | — | — | CN | disclosed |
| CN-113607945-B | Combination therapy of anti-HER 2 antibody-drug conjugates and Bcl-2 inhibitors | 豪夫迈·罗氏有限公司 | 2025-01-28 | — | — | CN | disclosed |
| CN-119365491-A | Chimeric antigen receptor based on CD30 hinge and/or transmembrane domain | 得克萨斯大学体系董事会 | 2025-01-24 | — | — | CN | disclosed |
| CN-119365201-A | Methods for activation and expansion of engineered natural killer cells and combinations with antibodies | 得克萨斯大学体系董事会 | 2025-01-24 | — | — | CN | disclosed |
| CN-119343447-A | Enhancing cell therapy activity in tumor microenvironments | 得克萨斯大学体系董事会 | 2025-01-21 | — | — | CN | disclosed |
| CN-114945377-B | Large scale combinatorial CAR transduction and CRISPR gene editing of MSC cells | 得克萨斯大学体系董事会 | 2024-11-12 | — | — | CN | disclosed |
| CN-111655726-B | Antifolate receptor alpha antibody conjugates and uses thereof | 苏特罗生物制药公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-118234744-A | Chimeric antigen receptor targeting HLA-G positive cancers | 得克萨斯大学体系董事会 | 2024-06-21 | — | — | CN | disclosed |
| CN-118005631-A | Tetrahydro-pyrido [3,4-b ] indole estrogen receptor modulators and uses thereof | 豪夫迈·罗氏有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-110872289-A | Novel 8-substituted imidazo [1,5-a ] pyridines as IDO1 and/or TDO inhibitors | 百济神州(北京)生物科技有限公司 | 2020-03-10 | — | — | CN | disclosed |
| CN-110698481-A | Heteroaryl pyridone and aza-pyridone amide compounds | 豪夫迈·罗氏有限公司 | 2020-01-17 | — | — | CN | disclosed |
| CN-107011348-B | Heteroaryl pyridone and aza-pyridone compounds as inhibitors of BTK activity | 霍夫曼-拉罗奇有限公司 | 2020-01-10 | — | — | CN | disclosed |
| CN-110627728-A | N- (cyanomethyl) -4- (2- (4-morpholinophenylamino) pyrimidin-4-yl) benzamide hydrochloride | 吉利德科学公司 | 2019-12-31 | — | — | CN | disclosed |
| US-9128097-B2 | Method and kit for assessing viable cells | CHEMOMETEC A/S (DK) | 2015-09-08 | — | — | US | disclosed |
| EP-0968309-B1 | METHOD FOR DETERMINING A NUCLEIC ACID | GEORGIA TECH RES INST (US) | 2004-10-13 | — | — | EP | disclosed |
| US-6225052-B1 | HYBRIDIZING NUCLEIC ACID TO SYNTHETIC HYBRIDIZATION PROBE WHICH HAS NON-NATURAL BACKBONE AND WHICH IS LABELED WITH ELECTRON DONOR AND/OR ELECTRON ACCEPTOR, THEN ACTIVATING AND DETECTING ELECTRON TRANSFER | ROCHE DIAGNOSTICS GMBH (DE) | 2001-05-01 | — | — | US | disclosed |
| EP-0968309-A2 | METHOD FOR DETERMINING A NUCLEIC ACID | GEORGIA TECH RESEARCH CORPORATION (US) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998037232-A2 | METHOD FOR DETERMINING A NUCLEIC ACID | GEORGIA TECH RESEARCH CORPORATION (US) | 1998-08-27 | — | — | WO | disclosed |
| CN-1150433-A | Diagnosis, therapy and cellular and animal models for diseases associated with mitochondrial defects | MITOKOR (US) | 1997-05-21 | — | — | CN | disclosed |