Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16254414 | 0.85 | — | — | |
| SCHEMBL12462077 | 0.85 | — | — | |
| SCHEMBL22756365 | 0.83 | PTPN1 (0.31) | PTPN1 | |
| SCHEMBL13160781 | 0.81 | FFAR1 (0.34) | FFAR1 | |
| Isopropyl Alcohol SCHEMBL28698445 | 0.78 | TSHR (0.35) | — | |
| SCHEMBL7955999 | 0.77 | — | — | |
| SCHEMBL15468834 | 0.76 | — | — | |
| SCHEMBL6962688 | 0.76 | — | — | |
| SCHEMBL5557996 | 0.76 | — | — | |
| SCHEMBL19743539 | 0.76 | FFAR1 (0.31) | FFAR1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12036209-B2 | Compounds and methods for the targeted degradation of Interleukin-1 receptor-associated kinase 4 polypeptides | ARVINAS OPERATIONS, INC. (US) | 2024-07-16 | — | — | US | disclosed |
| US-20220402907-A1 | MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE | YALE UNIVERSITY | 2022-12-22 | — | — | US | disclosed |
| US-20220388984-A1 | TETRAHYDRONAPHTHALENE AND TETRAHYDROISOQUINOLINE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS | ARVINAS OPERATIONS, INC. | 2022-12-08 | — | — | US | disclosed |
| US-11065231-B2 | Compounds and methods for the targeted degradation of interleukin-1 receptor- associated kinase 4 polypeptides | ARVINAS OPERATIONS, INC. (US) | 2021-07-20 | — | — | US | disclosed |
| US-10758534-B2 | Modulators of cystic fibrosis transmembrane conductance regulator | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2020-09-01 | — | — | US | disclosed |
| US-10604506-B2 | Modulators of estrogen receptor proteolysis and associated methods of use | ARVINAS OPERATIONS, INC. (US) | 2020-03-31 | — | — | US | disclosed |
| US-20190269683-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2019-09-05 | — | — | US | disclosed |
| US-20190151295-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 4 POLYPEPTIDES | ARVINAS OPERATIONS, INC. | 2019-05-23 | — | — | US | disclosed |
| US-9783573-B2 | IAP antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-10-10 | — | — | US | disclosed |
| US-9603889-B2 | IAP antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-03-28 | — | — | US | disclosed |
| EP-0847050-B1 | Optical recording medium | MITSUBISHI CHEM CORP (JP) | 2004-11-17 | — | — | EP | disclosed |
| WO-2004085408-A1 | 2, 3, 6-TRISUBSTITUTED-4-PYRIMIDONE DERIVATIVES | MITSUBISHI PHARMA CORPORATION (JP) | 2004-10-07 | — | — | WO | disclosed |
| EP-0847050-A2 | Optical recording medium | Mitsubishi Chemical Corporation (JP) | 1998-06-10 | — | — | EP | disclosed |
| EP-0313665-B1 | ACTINIC RADIATION-CURABLE COMPOSITION FOR CAST POLYMERIZATION AND PRODUCT OF CAST POLYMERIZATION | MITSUBISHI RAYON CO., LTD. (JP) | 1993-02-03 | — | — | EP | disclosed |
| EP-0210838-B1 | THERMAL DYE TRANSFER PRINTING SYSTEMS, THERMAL PRINTING SHEETS, AND DYE RECEIVING SHEETS | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1992-12-23 | — | — | EP | disclosed |
| US-4985399-A | SUBLIMABLE DYE AND LUBRICATING PARTICLES IN A RESIN BINDER | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| US-4902669-A | SUBLIMABLE DYE IN BINDER | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1990-02-20 | — | — | US | disclosed |
| EP-0313665-A4 | ACTINIC RADIATION-CURABLE COMPOSITION FOR CAST POLYMERIZATION AND PRODUCT OF CAST POLYMERIZATION. | MITSUBISHI RAYON CO (JP) | 1989-09-19 | — | — | EP | disclosed |
| WO-1988008434-A1 | ACTINIC RADIATION-CURABLE COMPOSITION FOR CAST POLYMERIZATION AND PRODUCT OF CAST POLYMERIZATION | MITSUBISHI RAYON CO., LTD. (JP) | 1988-11-03 | — | — | WO | disclosed |
| EP-0210838-A2 | Thermal dye transfer printing systems, thermal printing sheets, and dye receiving sheets | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1987-02-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190151295-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 4 POLYPEPTIDES | IRAK1, IRAK4, IRAK2 | FFAR1 3121/4885PTPN1 732/4885 |
| US-10604506-B2 | Modulators of estrogen receptor proteolysis and associated methods of use | ADRM1, MDM2, ESR2 | FFAR1 2981/4885PTPN1 2154/4885 |
| US-12036209-B2 | Compounds and methods for the targeted degradation of Interleukin-1 receptor-associated kinase 4 polypeptides | IRAK1, IRAK4, IRAK2 | FFAR1 3193/4885PTPN1 843/4885 |
| US-11065231-B2 | Compounds and methods for the targeted degradation of interleukin-1 receptor- associated kinase 4 polypeptides | IRAK1, IRAK4, IRAK2 | FFAR1 3121/4885PTPN1 732/4885 |
| US-20220388984-A1 | TETRAHYDRONAPHTHALENE AND TETRAHYDROISOQUINOLINE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS | MDM2, CRBN, VHL | FFAR1 3895/4885PTPN1 2714/4885 |
| US-20220402907-A1 | MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE | MDM2, CRBN, VHL | FFAR1 4582/4885PTPN1 2633/4885 |
| US-20190269683-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | CFTR, SCNN1B, SLC26A4 | FFAR1 823/4885PTPN1 1137/4885 |
| US-10758534-B2 | Modulators of cystic fibrosis transmembrane conductance regulator | CFTR, SCNN1B, SLC26A4 | FFAR1 823/4885PTPN1 1137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.