Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 2/20 | 0.32 |
| ▸ | KLK1 | P06870 | 2/20 | 0.32 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7245681 | 0.99 | TAAR1 (0.37) | TAAR1HTTALDH1A1HSP90AA1CASP7 | |
| SCHEMBL6680780 | 0.78 | PTPN11 (0.41) | HTTALDH1A1HSP90AA1CASP7CASP6 | |
| SCHEMBL6676196 | 0.78 | CA9 (0.45) | CA1CA2PLGKLK1KLK6 | |
| SCHEMBL6678278 | 0.78 | GHSR (0.45) | — | |
| Hydrochloric Acid SCHEMBL7246329 | 0.77 | GHSR (0.44) | — | |
| SCHEMBL6680162 | 0.76 | TAAR1 (0.39) | TAAR1HTTALDH1A1HSP90AA1CASP7 | |
| SCHEMBL6677724 | 0.75 | MEN1 (0.38) | ALDH1A1MEN1KMT2AMAPTCA1 | |
| Hydrochloric Acid SCHEMBL7245683 | 0.75 | TAAR1 (0.38) | TAAR1HTTALDH1A1HSP90AA1CASP7 | |
| Hydrochloric Acid SCHEMBL6677900 | 0.74 | MEN1 (0.37) | ALDH1A1MEN1KMT2AMAPTCA1 | |
| SCHEMBL6676402 | 0.72 | ROCK2 (0.41) | TAAR1ALDH1A1KIF11MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | claimed |