Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.51 |
| ▸ | PPARG | P37231 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6680171 | 1.00 | PPARA (0.51) | PPARAPPARGMEN1KMT2APPARD | |
| SCHEMBL6095313 | 0.85 | KMT2A (0.50) | PPARAPPARGMEN1KMT2AKCNA3 | |
| SCHEMBL6095311 | 0.85 | KMT2A (0.50) | PPARAPPARGMEN1KMT2AKCNA3 | |
| SCHEMBL6097182 | 0.85 | LMNA (0.54) | PPARAPPARGMEN1KMT2AKCNA3 | |
| SCHEMBL6094309 | 0.85 | LMNA (0.54) | PPARAPPARGMEN1KMT2AKCNA3 | |
| SCHEMBL6095014 | 0.78 | KMT2A (0.62) | MEN1KMT2ALMNAHPGD | |
| SCHEMBL6092690 | 0.78 | KMT2A (0.62) | MEN1KMT2ALMNAHPGD | |
| SCHEMBL6092685 | 0.78 | KMT2A (0.62) | MEN1KMT2ALMNAHPGD | |
| SCHEMBL6094413 | 0.75 | L3MBTL1 (0.55) | MEN1KMT2ALMNA | |
| SCHEMBL6094415 | 0.75 | L3MBTL1 (0.55) | MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1440052-A1 | BENZAMIDE DERIVATIVES AS ANTAGONISTS OF OREXIN RECEPTORS | SMITHKLINE BEECHAM PLC (GB) | 2004-07-28 | — | — | EP | disclosed |
| WO-2003037847-A1 | BENZAMIDE DERIVATIVES AS ANTAGONISTS OF OREXIN RECEPTORS | SMITHKLINE BEECHAM P.L.C. (GB) | 2003-05-08 | — | — | WO | disclosed |