Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6686050 | 0.95 | NCEH1 (0.45) | NCEH1POLBGAATDP1TLR8 | |
| SCHEMBL6684951 | 0.93 | LIPG (0.45) | NCEH1POLBGAATDP1TLR8 | |
| SCHEMBL6680888 | 0.93 | LIPG (0.45) | NCEH1POLBGAATDP1TLR8 | |
| SCHEMBL6679055 | 0.93 | LIPG (0.45) | NCEH1POLBGAATDP1TLR8 | |
| SCHEMBL6680376 | 0.89 | POLB (0.47) | NCEH1POLBGAATDP1NPC1 | |
| SCHEMBL7388022 | 0.82 | POLB (0.48) | NCEH1POLBGAATDP1NPC1 | |
| SCHEMBL8850092 | 0.81 | GABRA1 (0.52) | NCEH1POLBTDP1NPC1RAB9A | |
| SCHEMBL30640504 | 0.81 | GABRA1 (0.52) | NCEH1POLBTDP1NPC1RAB9A | |
| SCHEMBL2128314 | 0.80 | TSHR (0.48) | NCEH1GAATDP1L3MBTL1TLR8 | |
| SCHEMBL761100 | 0.80 | NCEH1 (0.51) | NCEH1GAATDP1L3MBTL1TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023214325-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES AND USES THEREOF AS TET2 INHIBITORS | NOVARTIS AG (CH) | 2023-11-09 | — | — | WO | disclosed |
| EP-0985649-B1 | Method for producing an aromatic compound having an alkyl group with at least three carbon atoms | TORAY INDUSTRIES (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-6462248-B1 | THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS | TORAY INDUSTRIES, INC. (JP) | 2002-10-08 | — | — | US | disclosed |
| EP-0985649-A2 | Method for producing an aromatic compound having an alkyl group with at least three carbon atoms | TORAY INDUSTRIES, INC. (JP) | 2000-03-15 | — | — | EP | disclosed |
| US-RE30279-E | FROM ALKYL OR ARYL HALIDE WITH HALO-SUBSTITUTED TRIVALENT PHOSPHORUS COMPOUNDS AND PHOSPHORUS PENTASULFIDE OR -OXIDE | STAUFFER CHEMICAL COMPANY (US) | 1980-05-20 | — | — | US | disclosed |
| US-4076746-A | FROM AN ALKYL OR ARYL HALIDE AND PHOSPHORUS SESQUISULFIDE | STAUFFER CHEMICAL COMPANY (US) | 1978-02-28 | — | — | US | disclosed |
| US-3989746-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | IKEDA MOHANDO CO., LTD. (JA) | 1976-11-02 | — | — | US | disclosed |