Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6684711 | 0.87 | GAA (0.55) | GAAMAPTMEN1KMT2ATDP1 | |
| SCHEMBL6682815 | 0.84 | TP53 (0.64) | GAAMAPTMEN1KMT2ATDP1 | |
| SCHEMBL6680826 | 0.81 | SIGMAR1 (0.55) | SIGMAR1MAOAMPOBCHE | |
| SCHEMBL27228 | 0.73 | GAA (0.95) | GAAMAPTMEN1KMT2ATDP1 | |
| SCHEMBL1785986 | 0.73 | KDM4E (0.51) | MPOHTR2AKDM4E | |
| SCHEMBL22495343 | 0.72 | GAA (0.58) | GAAMAPTMEN1KMT2ATDP1 | |
| Ammonia Solution, Strong SCHEMBL23581968 | 0.72 | GAA (0.91) | GAAMAPTMEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL1983401 | 0.72 | GAA (1.00) | GAAMAPTMEN1KMT2ATDP1 | |
| SCHEMBL25432637 | 0.72 | GAA (0.91) | GAAMAPTMEN1KMT2ATDP1 | |
| SCHEMBL11881258 | 0.72 | GAA (0.91) | GAAMAPTMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474431-A2 | MACROLIDE ANTIBACTERIAL COMPOUNDS | Abbott Laboratories (US) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003068790-A2 | MACROLIDE ANTIBACTERIAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2003-08-21 | — | — | WO | disclosed |