Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | CASR | P41180 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL79765 | 0.71 | SMN1; SMN2 (0.76) | POLBSIGMAR1SMN1; SMN2CASRMEN1 | |
| SCHEMBL774613 | 0.71 | SMN1; SMN2 (0.76) | POLBSIGMAR1SMN1; SMN2CASRMEN1 | |
| SCHEMBL11881252 | 0.71 | SMN1; SMN2 (0.70) | POLBSIGMAR1SMN1; SMN2CASRMEN1 | |
| SCHEMBL29560 | 0.71 | SMN1; SMN2 (0.76) | POLBSIGMAR1SMN1; SMN2CASRMEN1 | |
| SCHEMBL5875679 | 0.71 | POLB (0.44) | POLBSIGMAR1SMN1; SMN2CASRMEN1 | |
| Hydrochloric Acid SCHEMBL9635019 | 0.70 | SMN1; SMN2 (0.79) | POLBSIGMAR1SMN1; SMN2CASRMEN1 | |
| Hydrochloric Acid SCHEMBL27830673 | 0.70 | SMN1; SMN2 (0.79) | POLBSIGMAR1SMN1; SMN2CASRMEN1 | |
| Hydrochloric Acid SCHEMBL5493749 | 0.70 | SMN1; SMN2 (0.79) | POLBSIGMAR1SMN1; SMN2CASRMEN1 | |
| SCHEMBL27939948 | 0.70 | SMN1; SMN2 (0.73) | POLBSIGMAR1SMN1; SMN2CASRMEN1 | |
| SCHEMBL6418765 | 0.69 | SIGMAR1 (0.61) | POLBSIGMAR1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474431-A2 | MACROLIDE ANTIBACTERIAL COMPOUNDS | Abbott Laboratories (US) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003068790-A2 | MACROLIDE ANTIBACTERIAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2003-08-21 | — | — | WO | disclosed |