Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 6/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CKS1B | P61024 | 1/20 | 0.34 |
| ▸ | SKP1 | P63208 | 1/20 | 0.34 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6500770 | 0.86 | ITGB3 (0.41) | MAPKAPK2NR3C2HDAC1MAPK8CCR2 | |
| SCHEMBL7085612 | 0.86 | TAAR1 (0.40) | MAPKAPK2NQO2NR3C2GAAHPGD | |
| SCHEMBL28580348 | 0.83 | NQO2 (0.49) | NQO2NR3C2NAMPTLMNAGAA | |
| SCHEMBL6680383 | 0.79 | MAPKAPK2 (0.41) | MAPKAPK2NR3C2HDAC1NAMPTCCR2 | |
| SCHEMBL6492113 | 0.79 | MAPKAPK2 (0.40) | MAPKAPK2NR3C2HDAC1CCR2SCN9A | |
| SCHEMBL6492788 | 0.78 | NR3C2 (0.45) | MAPKAPK2NQO2NR3C2HDAC1MAPK8 | |
| SCHEMBL6499366 | 0.77 | NR3C2 (0.37) | MAPKAPK2NR3C2HDAC1CKS1BSKP1 | |
| SCHEMBL6499724 | 0.77 | ITGB3 (0.47) | LMNASCN9ACA1CA2 | |
| Hydrochloric Acid SCHEMBL28586309 | 0.77 | NR3C2 (0.44) | MAPKAPK2NQO2NR3C2HDAC1MAPK8 | |
| SCHEMBL6320838 | 0.74 | NR3C2 (0.43) | NQO2NR3C2LMNAGAAMAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472226-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003045921-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-05 | — | — | WO | disclosed |