Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 8/20 | 0.36 |
| ▸ | CKS1B | P61024 | 1/20 | 0.34 |
| ▸ | SKP1 | P63208 | 1/20 | 0.34 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6489886 | 0.87 | NR3C2 (0.39) | NR3C2MAPKAPK2CCR2HDAC1GLS | |
| SCHEMBL6499711 | 0.82 | SIRT1 (0.42) | MAPKAPK2CCR2HDAC1HDAC6 | |
| SCHEMBL6500770 | 0.80 | ITGB3 (0.41) | NR3C2MAPKAPK2CCR2HDAC1MAPK8 | |
| SCHEMBL29392374 | 0.80 | SSTR4 (0.34) | CKS1BSKP1SKP2HDAC1HDAC8 | |
| SCHEMBL23620907 | 0.80 | SSTR4 (0.34) | CKS1BSKP1SKP2HDAC1HDAC8 | |
| SCHEMBL6677518 | 0.79 | NR3C2 (0.39) | NR3C2HDAC1GLSHDAC8HDAC6 | |
| SCHEMBL6680383 | 0.79 | MAPKAPK2 (0.41) | NR3C2MAPKAPK2CCR2HDAC1GLS | |
| SCHEMBL6492788 | 0.78 | NR3C2 (0.45) | NR3C2MAPKAPK2CCR2HDAC1GLS | |
| SCHEMBL6680385 | 0.77 | MAPKAPK2 (0.38) | NR3C2MAPKAPK2CKS1BSKP1SKP2 | |
| SCHEMBL6501309 | 0.77 | TP53 (0.34) | HDAC1HDAC8HDAC6GSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | DAISO CO., LTD. (JP) | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | APOB, APOL1, CTRB2 | NR3C2 725/4885MAPKAPK2 3154/4885CKS1B 1120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.