Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HAT1 | O14929 | 6/20 | 0.37 |
| ▸ | EP300 | Q09472 | 6/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6269077 | 0.93 | ADRB3 (0.41) | KMT2ACA2MEN1GAAHAT1 | |
| SCHEMBL6272930 | 0.85 | ADRB3 (0.40) | CA2HAT1EP300ADRB1ADRB3 | |
| SCHEMBL6269328 | 0.82 | KDM4E (0.41) | KDM4ERAB9AKMT2AMEN1GAA | |
| SCHEMBL6679264 | 0.81 | ADRB3 (0.36) | KMT2ACA2MEN1ALDH1A1HAT1 | |
| SCHEMBL6678531 | 0.79 | ITGA4 (0.39) | KDM4EKMT2ACA2MEN1GAA | |
| SCHEMBL6679366 | 0.78 | ADRB3 (0.39) | CA2HAT1EP300ADRB1ADRB3 | |
| SCHEMBL6676099 | 0.78 | CA2 (0.54) | KDM4ERAB9ACA2 | |
| SCHEMBL6676373 | 0.78 | ADRB3 (0.40) | CA2ADRB1ADRB3 | |
| SCHEMBL6683334 | 0.77 | ADRB3 (0.42) | KMT2ACA2ADRB1ADRB3 | |
| SCHEMBL6273579 | 0.77 | BACE1 (0.41) | KDM4EKMT2AMEN1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004045610-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 2004-06-03 | — | — | WO | disclosed |