Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6666893 | 0.84 | NPC1 (0.74) | MAPTALDH1A1ADRA1ACYP2C9KMT2A | |
| SCHEMBL6666219 | 0.82 | MAPT (0.60) | MAPTALDH1A1ADRA1ACYP2C9KMT2A | |
| SCHEMBL6669899 | 0.80 | MAPT (0.56) | MAPTALDH1A1ADRA1ACYP2C9KMT2A | |
| SCHEMBL6670051 | 0.80 | KMT2A (0.59) | MAPTALDH1A1ADRA1ACYP2C9KMT2A | |
| SCHEMBL15831621 | 0.80 | ALDH1A1 (0.62) | MAPTALDH1A1ADRA1ACYP2C9KMT2A | |
| SCHEMBL6667070 | 0.80 | ALDH1A1 (0.63) | MAPTALDH1A1ADRA1ACYP2C9KMT2A | |
| SCHEMBL6668899 | 0.79 | HTT (0.60) | MAPTALDH1A1ADRA1ACYP2C9KMT2A | |
| SCHEMBL6680042 | 0.79 | MAPT (0.55) | MAPTALDH1A1ADRA1ACYP2C9KMT2A | |
| SCHEMBL6666442 | 0.79 | ALDH1A1 (0.69) | MAPTALDH1A1ADRA1ACYP2C9KMT2A | |
| SCHEMBL6669450 | 0.79 | ALDH1A1 (0.61) | MAPTALDH1A1ADRA1ACYP2C9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004021997-A2 | INHIBITORS OF FUNGAL INVASION | MICROBIA, INC. (US) | 2004-03-18 | — | — | WO | disclosed |