Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | PPIA | P62937 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12879697 | 0.84 | ALDH1A1 (0.77) | ALDH1A1MAPTADRA1ATSHRMAPK1 | |
| Sulfamethoxazole SCHEMBL3656 | 0.82 | ALDH1A1 (1.00) | ALDH1A1MAPTADRA1ATSHRMAPK1 | |
| SCHEMBL6690673 | 0.82 | PPIA (0.76) | ALDH1A1MAPTADRA1AHPGDTSHR | |
| Sulfamethoxazole SCHEMBL6896861 | 0.82 | ALDH1A1 (1.00) | ALDH1A1MAPTADRA1ATSHRMAPK1 | |
| SCHEMBL6667090 | 0.82 | ALDH1A1 (0.73) | ALDH1A1MAPTADRA1ATSHRMAPK1 | |
| SCHEMBL31469213 | 0.82 | ALDH1A1 (0.73) | ALDH1A1MAPTADRA1AHPGDTSHR | |
| SCHEMBL1027519 | 0.81 | TSHR (0.83) | ALDH1A1MAPTADRA1ATSHRMAPK1 | |
| Sulfamethoxazole SCHEMBL1368068 | 0.81 | ALDH1A1 (0.97) | ALDH1A1MAPTADRA1ATSHRMAPK1 | |
| Sulfamethoxazole SCHEMBL5870744 | 0.81 | ALDH1A1 (0.97) | ALDH1A1MAPTADRA1ATSHRMAPK1 | |
| Sulfamethoxazole SCHEMBL22467841 | 0.81 | ALDH1A1 (0.97) | ALDH1A1MAPTADRA1ATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11713290-B2 | Cycloheptylamine derivatives as anti-diabetic agents | UNITED ARAB EMIRATES UNIVERSITY (AE) | 2023-08-01 | — | — | US | disclosed |
| US-20210355074-A1 | CYCLOHEPTYLAMINE DERIVATIVES AS ANTI-DIABETIC AGENTS | UNITED ARAB EMIRATES UNIVERSITY (AE) | 2021-11-18 | — | — | US | disclosed |
| US-20210347725-A1 | CYCLOHEPTYLAMINE DERIVATIVES AS ANTI-DIABETIC AGENTS | UNITED ARAB EMIRATES UNIVERSITY (AE) | 2021-11-11 | — | — | US | disclosed |
| US-11091426-B1 | Cycloheptylamine derivatives as anti-diabetic agents | UNITED ARAB EMIRATES UNIVERSITY (AE) | 2021-08-17 | — | — | US | disclosed |
| WO-2004021997-A2 | INHIBITORS OF FUNGAL INVASION | MICROBIA, INC. (US) | 2004-03-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11713290-B2 | Cycloheptylamine derivatives as anti-diabetic agents | BHMT2, BHMT, GPR119 | ALDH1A1 940/4885MAPT 3567/4885ADRA1A 533/4885 |
| US-11091426-B1 | Cycloheptylamine derivatives as anti-diabetic agents | BHMT2, BHMT, GPR119 | ALDH1A1 940/4885MAPT 3567/4885ADRA1A 533/4885 |
| US-20210355074-A1 | CYCLOHEPTYLAMINE DERIVATIVES AS ANTI-DIABETIC AGENTS | BHMT2, BHMT, GPR119 | ALDH1A1 940/4885MAPT 3567/4885ADRA1A 533/4885 |
| US-20210347725-A1 | CYCLOHEPTYLAMINE DERIVATIVES AS ANTI-DIABETIC AGENTS | BHMT2, BHMT, GPR119 | ALDH1A1 940/4885MAPT 3567/4885ADRA1A 533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.