Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 10/20 | 0.41 |
| ▸ | PPARG | P37231 | 10/20 | 0.41 |
| ▸ | RARG | P13631 | 4/20 | 0.41 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | RARA | P10276 | 3/20 | 0.32 |
| ▸ | RARB | P10826 | 3/20 | 0.32 |
| ▸ | RXRB | P28702 | 3/20 | 0.32 |
| ▸ | RXRG | P48443 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5662542 | 1.00 | RXRA (0.41) | RXRAPPARGRARGTNFRSF1AALOX5 | |
| SCHEMBL5663920 | 0.85 | RXRA (0.38) | RXRAPPARGRARGTNFRSF1AALOX5 | |
| SCHEMBL6681261 | 0.83 | ALOX5 (0.44) | TNFRSF1AALOX5PTGS2KMT2ASMN1; SMN2 | |
| SCHEMBL5665712 | 0.83 | ALOX5 (0.44) | TNFRSF1AALOX5PTGS2KMT2ASMN1; SMN2 | |
| SCHEMBL5668478 | 0.82 | RARG (0.39) | RXRAPPARGRARGTNFRSF1AALOX5 | |
| SCHEMBL6916935 | 0.82 | TNFRSF1A (0.50) | TNFRSF1AKMT2ATP53MAPT | |
| SCHEMBL7065034 | 0.82 | TNFRSF1A (0.50) | TNFRSF1AKMT2ATP53MAPT | |
| SCHEMBL5663415 | 0.80 | RXRA (0.38) | RXRAPPARGRARGTNFRSF1AALOX5 | |
| SCHEMBL5667374 | 0.80 | RXRA (0.38) | RXRAPPARGRARGTNFRSF1AALOX5 | |
| SCHEMBL5664069 | 0.80 | CYP1A2 (0.38) | ALOX5PTGS2KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026243-A2 | THERAPEUTIC USES OF LINEAR KETOPHOSPHONATES | ILEX ONCOLOGY RESEARCH, SARL (CH) | 2004-04-01 | — | — | WO | disclosed |