Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | NT5E | P21589 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | NSD2 | O96028 | 3/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.38 |
| ▸ | SNCA | P37840 | 2/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PTPRA | P18433 | 1/20 | 0.37 |
| ▸ | PTPRB | P23467 | 1/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL633611 | 0.81 | CASP6 (0.36) | CASP6HSD17B10ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL7554551 | 0.78 | HTT (0.49) | ALDH1A1CYP2C9CYP2C19CYP1A2SNCA | |
| SCHEMBL9770840 | 0.76 | PTPN1 (0.44) | HSD17B10ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL30883035 | 0.74 | CA1 (0.46) | CASP6HSD17B10ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL29791468 | 0.74 | CA1 (0.46) | CASP6HSD17B10ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL17242206 | 0.74 | CA1 (0.46) | CASP6HSD17B10ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL30233294 | 0.70 | SNCA (0.62) | CASP6HSD17B10ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL305423 | 0.70 | SNCA (0.62) | CASP6HSD17B10ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL300937 | 0.70 | SNCA (0.62) | CASP6HSD17B10ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL29565260 | 0.70 | HSD17B10 (0.42) | HSD17B10ALDH1A1CYP2C9CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876428-B1 | SULFO BENZ e]INDOCYANINE FLUORESCENT DYES | INNOSENSE S R L (IT) | 2004-11-17 | — | — | EP | disclosed |
| US-6136612-A | THAT CAN BE EXCITED USING INEXPENSIVE LIGHT EMITTING DIODES AND DIODE LASERS, EXHIBIT GOOD WATER SOLUBILITY, AND CAN BE CONJUGATED TO A WIDE VARIETY OF MOLECULES OR SURFACES FOR LABELING PURPOSES; USE IN IMMUNOASSAY, DNA PROBES | SORIN BIOMEDICA CARDIO S.P.A. (IT) | 2000-10-24 | — | — | US | disclosed |