SCHEMBL9770840

SCHEMBL9770840

O=C(O)c1ccc2c3c(ccc2c1)N=CC3

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.44
ALDH1A1 P00352 4/20 0.41
KDM4E B2RXH2 3/20 0.41
HPGD P15428 2/20 0.41
ENPP2 Q13822 1/20 0.41
HSD17B10 Q99714 1/20 0.41
DPP4 P27487 1/20 0.38
GRIN2D O15399 1/20 0.38
GRIN2A Q12879 1/20 0.38
GRIN2C Q14957 1/20 0.38
TDP1 Q9NUW8 2/20 0.35
HSP90AA1 P07900 1/20 0.35
ESR2 Q92731 1/20 0.35
RARA P10276 2/20 0.35
RARB P10826 2/20 0.35
RARG P13631 2/20 0.35
PLAU P00749 1/20 0.35
CYP26A1 O43174 1/20 0.35
CYP26B1 Q9NR63 1/20 0.35
CSNK2A2 P19784 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6680937 0.76 CASP6 (0.46) PTPN1ALDH1A1HPGDHSD17B10TDP1
SCHEMBL7088722 0.74 PTPN1 (0.64) PTPN1ALDH1A1KDM4EHPGDENPP2
SCHEMBL3199131 0.74 ALDH1A1 (0.47) ALDH1A1KDM4EHPGDENPP2HSD17B10
SCHEMBL4389476 0.72 PTPN1 (0.50) PTPN1ALDH1A1KDM4EHPGDENPP2
SCHEMBL5138970 0.70 ALDH1A1 (0.47) ALDH1A1KDM4EHPGDENPP2HSD17B10
SCHEMBL30012690 0.70 HSD17B10 (0.42) ALDH1A1KDM4EHPGDHSD17B10TDP1
SCHEMBL29565260 0.70 HSD17B10 (0.42) ALDH1A1KDM4EHPGDHSD17B10TDP1
Iodide SCHEMBL30094907 0.68 HSD17B10 (0.41) ALDH1A1KDM4EHPGDHSD17B10TDP1
Hydrochloric Acid SCHEMBL29888500 0.68 HSD17B10 (0.41) ALDH1A1KDM4EHPGDHSD17B10TDP1
SCHEMBL24891572 0.68 KDM4E (0.50) PTPN1ALDH1A1KDM4EHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5030708-A Methine benzindole dyes as comonomers in polyesters; nontoxic; heat resistance; food and beverage containers and packaging; color intensity EASTMAN KODAK COMPANY (US) 1991-07-09 US disclosed