SCHEMBL6681010

SCHEMBL6681010

CCO[Si](OCC)(OCC)C(C(=O)O)c1ccc(N=Nc2ccccc2OC)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.43
MEN1 O00255 6/20 0.43
MAPT P10636 8/20 0.40
L3MBTL1 Q9Y468 4/20 0.40
NPSR1 Q6W5P4 2/20 0.40
GAA P10253 2/20 0.40
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
MBTPS1 Q14703 1/20 0.37
ALPL P05186 1/20 0.36
ALPG P10696 1/20 0.36
ANO1 Q5XXA6 1/20 0.36
ALDH1A1 P00352 4/20 0.36
TDP1 Q9NUW8 2/20 0.36
MAPK1 P28482 2/20 0.36
AKR1C3 P42330 1/20 0.36
AKR1C2 P52895 1/20 0.36
LMNA P02545 1/20 0.36
OPRK1 P41145 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL243131 0.83 MAPT (0.44) KMT2AMAPTL3MBTL1GAANPC1
SCHEMBL241081 0.78 MAPT (0.47) KMT2AMEN1MAPTL3MBTL1NPSR1
SCHEMBL4275809 0.75 KMT2A (0.40) KMT2AMEN1MAPTL3MBTL1NPSR1
SCHEMBL1405267 0.71 KMT2A (0.58) KMT2AMEN1MAPTL3MBTL1NPSR1
SCHEMBL31071661 0.71 KMT2A (0.58) KMT2AMEN1MAPTL3MBTL1NPSR1
SCHEMBL1405268 0.71 KMT2A (0.58) KMT2AMEN1MAPTL3MBTL1NPSR1
Fluoride SCHEMBL28089840 0.69 KMT2A (0.57) KMT2AMEN1MAPTL3MBTL1NPSR1
SCHEMBL28083613 0.69 NAMPT (0.39) KMT2AMEN1MAPTNPSR1GAA
SCHEMBL11145990 0.68 KMT2A (0.56) KMT2AMEN1MAPTL3MBTL1NPSR1
SCHEMBL11145988 0.68 KMT2A (0.56) KMT2AMEN1MAPTL3MBTL1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004044025-A2 ANTI-REFLECTIVE COATINGS FOR PHOTOLITHOGRAPHY AND METHODS OF PREPARATION THEREOF HONEYWELL INTERNATIONAL INC (US) 2004-05-27 WO disclosed