Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CCL2 | P13500 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29603716 | 1.00 | SIGMAR1 (0.38) | SIGMAR1HTR2AHTR6KDM4ECYP2D6 | |
| SCHEMBL6904952 | 0.98 | SIGMAR1 (0.37) | SIGMAR1HTR2AHTR6KDM4ECYP2D6 | |
| SCHEMBL8770693 | 0.98 | SIGMAR1 (0.37) | SIGMAR1HTR2AHTR6KDM4ECYP2D6 | |
| Lithium SCHEMBL8770699 | 0.98 | SIGMAR1 (0.37) | SIGMAR1HTR2AHTR6KDM4ECYP2D6 | |
| SCHEMBL9144863 | 0.98 | SIGMAR1 (0.37) | SIGMAR1HTR2AHTR6KDM4ECYP2D6 | |
| SCHEMBL9144870 | 0.98 | SIGMAR1 (0.37) | SIGMAR1HTR2AHTR6KDM4ECYP2D6 | |
| Hydrochloric Acid SCHEMBL7640182 | 0.96 | SIGMAR1 (0.36) | SIGMAR1HTR2AHTR6KDM4ECYP2D6 | |
| Hydrochloric Acid SCHEMBL7899361 | 0.96 | SIGMAR1 (0.36) | SIGMAR1HTR2AHTR6KDM4ECYP2D6 | |
| Hydrochloric Acid SCHEMBL6904140 | 0.96 | SIGMAR1 (0.36) | SIGMAR1HTR2AHTR6KDM4ECYP2D6 | |
| SCHEMBL7711844 | 0.94 | SIGMAR1 (0.35) | SIGMAR1HTR2AHTR6KDM4ECYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 264 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920432-B1 | PREPARATION AND SEPARATION OF RAC AND MESO COMPOUND MIXTURES | BOULDER SCIENT CO (US) | 2005-08-17 | — | — | EP | claimed |
| JP-2004514033-A | — | — | 2004-05-13 | — | — | JP | claimed |
| EP-0835886-B1 | Process for preparing and using meso/racemic-(bis(indenyl)ethane)zirconium dichloride compounds | ATOFINA RES (BE) | 2004-02-25 | — | — | EP | claimed |
| EP-1334137-A2 | CATALYST SYSTEM AND ITS USE IN OLEFIN POLYMERIZATION | Univation Technologies LLC (US) | 2003-08-13 | — | — | EP | claimed |
| US-6605563-B1 | Bulky ligand metallocene catalyst, an alumoxane activator, a Group 13 element containing first modifier, and a cycloalkadiene second modifier | UNIVATION TECHNOLOGIES, LLC | 2003-08-12 | — | — | US | claimed |
| US-20030149202-A1 | CATALYST SYSTEM AND ITS USE IN OLEFIN POLYMERIZATION | KAO SUN-CHUEH (US) | 2003-08-07 | — | — | US | claimed |
| US-6552137-B1 | Polymerization olefin(s) in the presence of a catalyst system comprising: bulky ligand metallocene catalyst compound; first modifier comprising a Group 13 element containing compound; second modifier comprising a cycloalkadiene and activator | UNIVATION TECHNOLOGIES, LLC | 2003-04-22 | — | — | US | claimed |
| US-20020115801-A1 | Process for preparing and using meso/racemic-[bis (indenyl) ethane] zirconium dichloride compounds | RAZAVI ABBAS (BE) | 2002-08-22 | — | — | US | claimed |
| WO-2002040555-A2 | CATALYST SYSTEM AND ITS USE IN OLEFIN POLYMERIZATION | UNIVATION TECHNOLOGIES, LLC (US) | 2002-05-23 | — | — | WO | claimed |
| EP-0920432-A4 | PREPARATION AND SEPARATION OF RAC AND MESO COMPOUND MIXTURES | BOULDER SCIENT CO (US) | 2001-08-16 | — | — | EP | claimed |
| EP-0835886-A1 | Process for preparing and using meso/racemic-(bis(indenyl)ethane)zirconium dichloride compounds | FINA RESEARCH S.A. (BE) | 1998-04-15 | — | — | EP | claimed |
| US-5707914-A | ZIRCONIUM OR HAFNIUM ALKYLS OR ALKOXIDES | NIPPON OIL CO., LTD. (JP) | 1998-01-13 | — | — | US | claimed |
| US-5677401-A | COORDINATION CATALYST | NIPPON OIL CO., LTD. (JP) | 1997-10-14 | — | — | US | claimed |
| US-5670588-A | TITANIUM, ZIRCONIUM, OR HAFNIUM COMPOUND, ORGANOCYCLIC HYDROCARBON OR SIICON COMPOUND, MODIFIED ORGANOALUMINUM COMPOUND | NIPPON OIL CO., LTD. (JP) | 1997-09-23 | — | — | US | claimed |
| US-5670681-A | Process for preparing a carbon-bridged biscyclopentadiene compound | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-23 | — | — | US | claimed |
| US-5643845-A | HAFNIUM OR ZIRCONIUM COMPOUND AND A CYCLOPENTADIENE OR INDENE COMPOUND, HIGH MOLECULAR WEIGHT | NIPPON OIL CO., LTD. (JP) | 1997-07-01 | — | — | US | claimed |
| US-5625014-A | Method for polymerization of olefins | NIPPON OIL CO., LTD. (JP) | 1997-04-29 | — | — | US | claimed |
| WO-1997014727-A1 | HOMOGENEOUS METALLOCENE-BASED OLEFIN POLYMERIZATION SYSTEM WITH INCREASED ACTIVITY | AMOCO CORPORATION (US) | 1997-04-24 | — | — | WO | claimed |
| US-5594082-A | COORDINATION CATALYST, ALUMOXANE, CYCLOPENTADIENE, INDENE, AZULENE OR FLUORENE COMPOUND | NIPPON OIL CO., LTD. (JP) | 1997-01-14 | — | — | US | claimed |
| US-5451555-A | Catalyst components for polymerization of olefins | NIPPON OIL CO., LTD. (JP) | 1995-09-19 | — | — | US | claimed |