Hydrochloric Acid

Hydrochloric Acid

SCHEMBL7899361

CC(C1C=Cc2ccccc21)C1C=Cc2ccccc21.[Cl-].[Cl-].[Hf+2]

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 known ✓ P08172 1/20 0.33
CHRM1 known ✓ P11229 1/20 0.33
CHRM3 known ✓ P20309 1/20 0.33
SLC6A2 known ✓ P23975 1/20 0.33
SLC6A3 known ✓ Q01959 1/20 0.33
SIGMAR1 Q99720 6/20 0.36
HTR2A P28223 2/20 0.35
HTR6 P50406 1/20 0.35
KDM4E B2RXH2 2/20 0.33
BRD4 O60885 1/20 0.33
CCL2 P13500 1/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
DRD2 P14416 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
NFKB1 P19838 1/20 0.33
HTR2C P28335 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6904140 0.96 SIGMAR1 (0.36) SIGMAR1HTR2AHTR6KDM4EBRD4
SCHEMBL668104 0.96 SIGMAR1 (0.38) SIGMAR1HTR2AHTR6KDM4EBRD4
SCHEMBL29603716 0.96 SIGMAR1 (0.38) SIGMAR1HTR2AHTR6KDM4EBRD4
SCHEMBL9144863 0.94 SIGMAR1 (0.37) SIGMAR1HTR2AHTR6KDM4EBRD4
SCHEMBL8770693 0.94 SIGMAR1 (0.37) SIGMAR1HTR2AHTR6KDM4EBRD4
SCHEMBL9144870 0.94 SIGMAR1 (0.37) SIGMAR1HTR2AHTR6KDM4EBRD4
SCHEMBL6904952 0.94 SIGMAR1 (0.37) SIGMAR1HTR2AHTR6KDM4EBRD4
Lithium SCHEMBL8770699 0.94 SIGMAR1 (0.37) SIGMAR1HTR2AHTR6KDM4EBRD4
Hydrochloric Acid SCHEMBL7640182 0.92 SIGMAR1 (0.36) SIGMAR1HTR2AHTR6KDM4EBRD4
SCHEMBL7711844 0.90 SIGMAR1 (0.35) SIGMAR1HTR2AHTR6KDM4EBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6291601-B1 HOMOPOLYMERISATION OF ETHYLENE AND HYDROGEN IN REACTOR IN THE PRESENCE OF METALLOCENE CATALYST TO PRODUCE POLYETHYLENE PRODUCT WHICH IS REACTED WITH ALPHA-OLEFIN IN SECOND REACTOR TO PRODUCE COPOLYMERIZED PRODUCT IN PRESENCE OF CATALYST FINA RESEARCH, S.A. (BE) 2001-09-18 US disclosed