Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6680479 | 0.85 | CYP2C9 (0.39) | CYP2C9PTGER1LMNAMEN1KMT2A | |
| SCHEMBL6680190 | 0.83 | SYK (0.35) | CYP2C9PTGER1KDM4EMEN1MAPT | |
| SCHEMBL6678139 | 0.81 | CYP2C9 (0.40) | CYP2C9PTGER1USP2LMNAKDM4E | |
| SCHEMBL6680549 | 0.78 | HDAC8 (0.40) | KDM4EMEN1MAPTKMT2AHDAC8 | |
| SCHEMBL6675702 | 0.77 | CYP2C9 (0.43) | CYP2C9PTGER1USP2LMNAKDM4E | |
| SCHEMBL6681039 | 0.76 | C5AR1 (0.39) | CYP2C9PTGER1KDM4EC5AR1MEN1 | |
| SCHEMBL6678137 | 0.74 | C5AR1 (0.46) | CYP2C9PTGER1LMNAKDM4EC5AR1 | |
| SCHEMBL6674836 | 0.73 | KDM4E (0.34) | KDM4EMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL6678687 | 0.72 | KDM4E (0.38) | KDM4EMAPTALDH1A1HPGDCNR2 | |
| SCHEMBL6679124 | 0.72 | NR1H4 (0.44) | LMNAKMT2AHDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | disclosed |
| EP-0798292-A1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | Chugai Seiyaku Kabushiki Kaisha (JP) | 1997-10-01 | — | — | EP | disclosed |