Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678687 | 0.91 | KDM4E (0.38) | KDM4ENPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL6680479 | 0.89 | CYP2C9 (0.39) | KMT2APPARDPPARGMEN1OPRK1 | |
| SCHEMBL6676958 | 0.87 | KDM4E (0.36) | KDM4ENPC1MAPTRAB9AL3MBTL1 | |
| SCHEMBL6677105 | 0.80 | KDM4A (0.36) | KDM4ENPC1MAPTRAB9AKMT2A | |
| SCHEMBL8771555 | 0.78 | IDO1 (0.39) | KDM4ENPC1MAPTRAB9ACA1 | |
| SCHEMBL6687614 | 0.77 | IDO1 (0.41) | KDM4ENPC1MAPTRAB9AKMT2A | |
| SCHEMBL6681075 | 0.77 | NQO2 (0.39) | KDM4ENPC1MAPTRAB9AKMT2A | |
| SCHEMBL6675899 | 0.77 | KDM4E (0.37) | KDM4ENPC1MAPTRAB9AKMT2A | |
| SCHEMBL6681092 | 0.77 | ALDH1A1 (0.42) | KDM4EMAPTKMT2AALDH1A1CYP2D6 | |
| SCHEMBL6676118 | 0.76 | CA2 (0.47) | KDM4ENPC1MAPTRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | disclosed |
| EP-0798292-A1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | Chugai Seiyaku Kabushiki Kaisha (JP) | 1997-10-01 | — | — | EP | disclosed |