Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CES2 | O00748 | 4/20 | 0.47 |
| ▸ | CES1 | P23141 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8971856 | 0.80 | L3MBTL1 (0.67) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7908984 | 0.80 | L3MBTL1 (0.67) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL8972353 | 0.80 | L3MBTL1 (0.67) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL12702680 | 0.80 | ALDH1A1 (0.49) | HTTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL8971899 | 0.80 | L3MBTL1 (0.67) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL474080 | 0.80 | L3MBTL1 (0.67) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL8973343 | 0.80 | L3MBTL1 (0.67) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL2982115 | 0.80 | L3MBTL1 (0.67) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL8972298 | 0.80 | L3MBTL1 (0.67) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL8972793 | 0.80 | L3MBTL1 (0.67) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1417196-A1 | DNA-PK INHIBITORS | Cancer Research Technology Limited (GB) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003024949-A1 | DNA-PK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2003-03-27 | — | — | WO | disclosed |