Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 16/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5262987 | 0.86 | TRPV1 (0.44) | TRPV1KCNA5 | |
| SCHEMBL5262991 | 0.86 | TRPV1 (0.44) | TRPV1KCNA5 | |
| SCHEMBL5259747 | 0.85 | MEN1 (0.43) | TRPV1KCNA5 | |
| SCHEMBL5259734 | 0.85 | MEN1 (0.43) | TRPV1KCNA5 | |
| SCHEMBL5259289 | 0.80 | CA12 (0.42) | TRPV1 | |
| SCHEMBL5259291 | 0.80 | CA12 (0.42) | TRPV1 | |
| SCHEMBL5262880 | 0.79 | MEN1 (0.46) | NAMPT | |
| SCHEMBL5261648 | 0.79 | MEN1 (0.46) | NAMPT | |
| SCHEMBL5259740 | 0.77 | TRPV1 (0.41) | TRPV1NAMPTKCNA5 | |
| SCHEMBL6667466 | 0.76 | TRPV1 (0.40) | TRPV1NAMPTMAPK1KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383750-A2 | UREA DERIVATIVES AS INTEGRIN ALPHA 4 ANTAGONISTS | Almirall Prodesfarma, S.A. (ES) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002057242-A2 | UREA DERIVATIVES AS INTEGRIN ALPHA 4 ANTAGONISTS | ALMIRALL PRODESFARMA, S.A. (ES) | 2002-07-25 | — | — | WO | disclosed |