Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.66 |
| ▸ | NPC1 | O15118 | 11/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.66 |
| ▸ | MAPT | P10636 | 6/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | CASP3 | P42574 | 1/20 | 0.62 |
| ▸ | ELANE | P08246 | 1/20 | 0.57 |
| ▸ | MMP2 | P08253 | 2/20 | 0.53 |
| ▸ | MMP9 | P14780 | 2/20 | 0.53 |
| ▸ | MMP8 | P22894 | 2/20 | 0.53 |
| ▸ | MMP13 | P45452 | 2/20 | 0.53 |
| ▸ | GABRP | O00591 | 1/20 | 0.52 |
| ▸ | GABRD | O14764 | 1/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.52 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6682494 | 0.90 | RAB9A (0.67) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL29531637 | 0.90 | RAB9A (0.67) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL3137128 | 0.89 | RAB9A (0.82) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL4053590 | 0.85 | RAB9A (0.66) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL2491306 | 0.84 | MMP2 (0.72) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL4056629 | 0.83 | RAB9A (0.63) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL3962448 | 0.81 | RAB9A (0.65) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL7921287 | 0.81 | RAB9A (0.82) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL4052337 | 0.80 | RAB9A (0.59) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL2246143 | 0.80 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004067480-A2 | SUBSTITUTED PHENYLUREA DERIVATIVES AS HDAC INHIBITORS | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2004-08-12 | — | — | WO | disclosed |
| WO-2004067480-A2 | SUBSTITUTED PHENYLUREA DERIVATIVES AS HDAC INHIBITORS | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2004-08-12 | — | — | WO | disclosed |