SCHEMBL6681540

SCHEMBL6681540

CCCCOc1[c]c[c]cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 4/20 0.36
CYP1A2 P05177 3/20 0.35
CYP2C9 P11712 3/20 0.35
CYP2C19 P33261 3/20 0.35
NR5A1 Q13285 1/20 0.35
RAB9A P51151 3/20 0.35
GAA P10253 2/20 0.35
CYP2D6 P10635 3/20 0.34
CYP3A4 P08684 2/20 0.34
CYP19A1 P11511 2/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
TSHR P16473 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
LMNA P02545 2/20 0.33
NPC1 O15118 1/20 0.33
TP53 P04637 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6685617 0.93 NR5A1 (0.41) LTA4HNR5A1RAB9AGAATSHR
SCHEMBL7679263 0.93 NR5A1 (0.41) LTA4HNR5A1RAB9AGAATSHR
SCHEMBL6684072 0.93 NR5A1 (0.41) LTA4HNR5A1RAB9AGAATSHR
SCHEMBL10494423 0.90 MEN1 (0.33) LTA4HGAACA12CA1CA2
SCHEMBL1374744 0.82
SCHEMBL6681485 0.81 TSHR (0.32) TSHR
SCHEMBL11763733 0.80 KDM4E (0.43) CYP1A2CYP2C19CYP2D6KDM4EALDH1A1
SCHEMBL8371561 0.78 ALDH1A1 (0.38) GAAALDH1A1
SCHEMBL49991 0.74 LTA4H (0.46) LTA4HCYP1A2CYP2C9CYP2C19NR5A1
SCHEMBL27670047 0.73 LTA4H (0.44) LTA4HCYP1A2CYP2C9CYP2C19NR5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1132770-B1 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO LTD (JP) 2004-11-17 EP disclosed
US-6492100-B2 Silver halide color photographic lightsensitive material and compound used therein FUJI PHOTO FILM CO., LTD. (JP) 2002-12-10 US disclosed
US-6468729-B2 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 2002-10-22 US disclosed
US-20020051948-A1 Silver halide color photographic lightsensitive material and compound used therein FUJIFILM CORPORATION (JP) 2002-05-02 US disclosed
US-20010031433-A1 Silver halide photographic light-sensitive material FUJIFILM CORPORATION (JP) 2001-10-18 US disclosed
EP-1132770-A2 Silver halide photographic light-sensitive material Fuji Photo Film Co., Ltd. (JP) 2001-09-12 EP disclosed
US-4602093-A ADRENERGIC BLOCKING AGENTS MERCK & CO., INC. (US) 1986-07-22 US disclosed