Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 9/20 | 0.48 |
| ▸ | CDC25A | P30304 | 7/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.48 |
| ▸ | S100A4 | P26447 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | BLM | P54132 | 3/20 | 0.44 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.44 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31238243 | 1.00 | CDC25B (0.48) | CDC25BCDC25AAURKAAURKBS100A4 | |
| SCHEMBL571026 | 0.75 | CDC25B (0.68) | CDC25BCDC25AAURKAAURKBS100A4 | |
| SCHEMBL29941466 | 0.75 | CDC25B (0.68) | CDC25BCDC25AAURKAAURKBS100A4 | |
| Water SCHEMBL8664586 | 0.73 | CDC25B (0.65) | CDC25BCDC25AAURKAAURKBS100A4 | |
| SCHEMBL22874151 | 0.72 | CDC25B (0.54) | CDC25BCDC25AAURKAAURKBS100A4 | |
| SCHEMBL7915423 | 0.72 | CDC25B (0.48) | CDC25BCDC25AAURKAAURKBS100A4 | |
| SCHEMBL15491792 | 0.71 | CDC25B (0.62) | CDC25BCDC25AAURKAAURKBS100A4 | |
| SCHEMBL5822470 | 0.69 | CDC25B (0.50) | CDC25BCDC25AAURKAAURKBS100A4 | |
| SCHEMBL1556617 | 0.69 | CDC25B (0.60) | CDC25BCDC25AAURKAAURKBS100A4 | |
| SCHEMBL12761943 | 0.68 | AURKA (0.48) | CDC25BCDC25AAURKAAURKBS100A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004047925-A2 | THERAPEUTIC OXIDATION CATALYSTS | EXETER ANTIOXIDANT THERAPEUTICS LIMITED (GB) | 2004-06-10 | — | — | WO | disclosed |