Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 15/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 13/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 11/20 | 0.42 |
| ▸ | NNMT | P40261 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14199932 | 0.82 | OPRM1 (0.42) | OPRM1OPRK1OPRD1NNMTABCB1 | |
| SCHEMBL1532891 | 0.82 | OPRM1 (0.51) | OPRM1OPRK1OPRD1NNMTGRIN2D | |
| SCHEMBL3699746 | 0.81 | OPRM1 (0.43) | OPRM1OPRK1OPRD1NNMTABCB1 | |
| SCHEMBL3690095 | 0.81 | OPRM1 (0.55) | OPRM1OPRK1OPRD1NNMTABCB1 | |
| SCHEMBL13773087 | 0.80 | OPRM1 (0.41) | OPRM1OPRK1OPRD1NNMTABCB1 | |
| SCHEMBL13840078 | 0.80 | OPRM1 (0.40) | OPRM1OPRK1OPRD1NNMTABCB1 | |
| SCHEMBL3695129 | 0.79 | NNMT (0.48) | OPRM1OPRK1OPRD1NNMTABCB1 | |
| SCHEMBL6224920 | 0.78 | OPRM1 (0.43) | OPRM1OPRK1OPRD1NNMTGRIN2D | |
| SCHEMBL6203883 | 0.77 | OPRM1 (0.43) | OPRM1OPRK1OPRD1GRIN2DGRIN3B | |
| SCHEMBL3692171 | 0.73 | OPRM1 (0.55) | OPRM1OPRK1OPRD1NNMTGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026305-A9 | DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONIST | LILLY CO ELI (US) | 2004-05-13 | — | — | WO | disclosed |