Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of 1-Pentanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.92 |
| ▸ | TSHR | P16473 | 5/20 | 0.86 |
| ▸ | LMNA | P02545 | 4/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.86 |
| ▸ | MEN1 | O00255 | 2/20 | 0.86 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.86 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.86 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1-Pentanol SCHEMBL724430 | 1.00 | — | — | |
| Cetyl Alcohol SCHEMBL1101785 | 0.96 | ALDH1A1 (0.93) | SMN1; SMN2TSHRLMNAALDH1A1MEN1 | |
| Cetyl Alcohol SCHEMBL873050 | 0.96 | ALDH1A1 (0.93) | SMN1; SMN2TSHRLMNAALDH1A1MEN1 | |
| Triacontanol SCHEMBL5609342 | 0.96 | ALDH1A1 (0.93) | SMN1; SMN2TSHRLMNAALDH1A1MEN1 | |
| Decanol SCHEMBL10594393 | 0.96 | ALDH1A1 (0.93) | SMN1; SMN2TSHRLMNAALDH1A1MEN1 | |
| Undecanol SCHEMBL4656406 | 0.96 | ALDH1A1 (0.93) | SMN1; SMN2TSHRLMNAALDH1A1MEN1 | |
| Docosanol SCHEMBL4958624 | 0.96 | ALDH1A1 (0.93) | SMN1; SMN2TSHRLMNAALDH1A1MEN1 | |
| Myristyl Alcohol SCHEMBL2046092 | 0.96 | ALDH1A1 (0.93) | SMN1; SMN2TSHRLMNAALDH1A1MEN1 | |
| Nonanol SCHEMBL2761019 | 0.96 | ALDH1A1 (0.93) | SMN1; SMN2TSHRLMNAALDH1A1MEN1 | |
| Alcohol SCHEMBL5138742 | 0.96 | ALDH1A1 (0.93) | SMN1; SMN2TSHRLMNAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230394-A1 | AQUEOUS POLYMER DISPERSIONS FOR ADHESIVES | Wacker Chemie AG (DE) | 2017-10-18 | — | — | EP | claimed |
| WO-2016113211-A1 | AQUEOUS POLYMER DISPERSIONS FOR ADHESIVES | WACKER CHEMIE AG (DE) | 2016-07-21 | — | — | WO | claimed |
| EP-2000485-B1 | Formaldehyde-free emulsion polymer dispersion composition including fully hydrolyzed polyvinyl alcohol as colloidal stabilizer provding improved heat resistance | WACKER CHEMICAL CORP (US) | 2010-08-11 | — | — | EP | claimed |
| US-4284506-A | POLYURETHANES | NL INDUSTRIES, INC. (US) | 1981-08-18 | — | — | US | claimed |
| US-4238592-A | Method for production of duroplastic, single-component polyurethanes | CHEMISCHE WERKE HULS AG (DE) | 1980-12-09 | — | — | US | claimed |
| WO-2022004249-A1 | MULTILAYERED POLYESTER FILM | 東洋紡株式会社 | 2022-01-06 | — | — | WO | disclosed |
| EP-3230394-A1 | AQUEOUS POLYMER DISPERSIONS FOR ADHESIVES | Wacker Chemie AG (DE) | 2017-10-18 | — | — | EP | disclosed |
| WO-2016113211-A1 | AQUEOUS POLYMER DISPERSIONS FOR ADHESIVES | WACKER CHEMIE AG (DE) | 2016-07-21 | — | — | WO | disclosed |
| EP-2421818-B1 | METHOD FOR PRODUCING COLOR-STABLE MDA AND MDI | BASF SE (DE) | 2014-08-27 | — | — | EP | disclosed |
| US-8614352-B2 | Method for producing color-stable MDA and MDI | BASF SE (DE) | 2013-12-24 | — | — | US | disclosed |
| EP-2421818-A1 | METHOD FOR PRODUCING COLOR-STABLE MDA AND MDI | BASF SE (DE) | 2012-02-29 | — | — | EP | disclosed |
| US-20120046497-A1 | METHOD FOR PRODUCING COLOR-STABLE MDA AND MDI | BASF SE (DE) | 2012-02-23 | — | — | US | disclosed |
| EP-0445602-A2 | Process for the preparation of mixtures of diphenylmethane-diisocyanates and polyphenylmethylene-polyisocyanates with a reduced iodic colorimetric measure | BASF Aktiengesellschaft (DE) | 1991-09-11 | — | — | EP | disclosed |
| EP-0344512-A2 | Liquid protective coating for concrete surfaces | W.R. Grace & Co.-Conn. (US) | 1989-12-06 | — | — | EP | disclosed |
| US-4877829-A | POLYURETHANE CONTAINING CASTOR OIL, LOW MOLECULAR WEIGHT POLYOL, ELASTOMER, DIPHENYLMETHANE DIISOCYANATE | W. R. GRACE & CO.-CONN. (US) | 1989-10-31 | — | — | US | disclosed |
| US-4855185-A | APPLYING MEMBRANE COMPOSED OF LOW MOLECULAR WEIGHT POLYOL, POLYOXYPROPYLENETRIOL, ELASTOMER REACTED WITH POLYISOCYANATE MIXTURE | W. R. GRACE & CO.-CONN. (US) | 1989-08-08 | — | — | US | disclosed |
| US-4788269-A | POLYOL MONOMER, POLYOXYPROPYLENE TRIOL, ELASTOMER, DIPHENYLMETHANE DIISOCYANATE | W. R. GRACE & CO.-CONN. (US) | 1988-11-29 | — | — | US | disclosed |
| US-4405725-A | Foamed polyisocyanurates | MOBAY CHEMICAL CORPORATION (US) | 1983-09-20 | — | — | US | disclosed |
| US-4284506-A | POLYURETHANES | NL INDUSTRIES, INC. (US) | 1981-08-18 | — | — | US | disclosed |
| US-4064087-A | WITHOUT BUFFERS, FREE RADICAL CATALYSTS, ADDITION POLYMERIZATION ON | PPG INDUSTRIES, INC. (US) | 1977-12-20 | — | — | US | disclosed |