Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Docosanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.93 |
| ▸ | TSHR | P16473 | 4/20 | 0.93 |
| ▸ | LMNA | P02545 | 3/20 | 0.93 |
| ▸ | MEN1 | O00255 | 2/20 | 0.93 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.93 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.93 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.86 |
| ▸ | THRB | P10828 | 2/20 | 0.57 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 3/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cetostearyl Alcohol SCHEMBL1643143 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| Myristyl Alcohol SCHEMBL2046092 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| Cetyl Alcohol SCHEMBL1101785 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| Triacontanol SCHEMBL5609342 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| Decanol SCHEMBL10594393 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| Nonanol SCHEMBL2761019 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| Alcohol SCHEMBL5138742 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| Cetyl Alcohol SCHEMBL873050 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| Undecanol SCHEMBL4656406 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| Alcohol SCHEMBL872545 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TSHRLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777759-A | Modified optically variable dye and preparation method thereof | 湖南肆玖科技有限公司 | 2024-03-29 | — | — | CN | claimed |
| EP-3638251-B1 | BISPHOSPHOCIN GEL FORMULATIONS AND USES THEREOF | LAKEWOOD AMEDEX INC (US) | 2024-03-06 | — | — | EP | claimed |
| EP-4241769-A2 | BISPHOSPHOCIN GEL FORMULATIONS AND USES THEREOF | Lakewood Amedex, Inc. (US) | 2023-09-13 | — | — | EP | claimed |
| US-20230125677-A1 | BISPHOSPHOCIN GEL FORMULATIONS AND USES THEREOF | LAKEWOOD AMEDEX INC (US) | 2023-04-27 | — | — | US | claimed |
| US-20210361689-A1 | BISPHOSPHOCIN GEL FORMULATIONS AND USES THEREOF | Lakewood Amedex, Inc. | 2021-11-25 | — | — | US | claimed |
| US-20200360415-A1 | BISPHOSPHOCIN GEL FORMULATIONS AND USES THEREOF | Lakewood Amedex, Inc. | 2020-11-19 | — | — | US | claimed |
| EP-3638251-A1 | BISPHOSPHOCIN GEL FORMULATIONS AND USES THEREOF | Lakewood Amedex, Inc. (US) | 2020-04-22 | — | — | EP | claimed |
| WO-2018231863-A1 | BISPHOSPHOCIN GEL FORMULATIONS AND USES THEREOF | LAKEWOOD AMEDEX, INC (US) | 2018-12-20 | — | — | WO | claimed |
| US-20180353529-A1 | BISPHOSPHOCIN GEL FORMULATIONS AND USES THEREOF | Lakewood Amedex, Inc. | 2018-12-13 | — | — | US | claimed |
| CN-108530639-A | Efficient water-coal-slurry thinner | 青岛艾尔乐新材料有限公司 | 2018-09-14 | — | — | CN | claimed |
| CN-101353827-B | Multi-stage phase change micro-nano complex fiber, and preparation method and application thereof | CHINESE ACAD INST CHEMISTRY | 2010-12-29 | — | — | CN | claimed |
| CN-101353827-A | Multi-stage phase change micro-nano complex fiber, and preparation method and application thereof | CHINESE ACAD INST CHEMISTRY (CN) | 2009-01-28 | — | — | CN | claimed |
| US-6440980-B1 | Synergistic inhibition of viral replication by long-chain hydrocarbons and nucleoside analogs | AVANIR PHARMACEUTICALS | 2002-08-27 | — | — | US | claimed |
| EP-0514009-B1 | Corneal treatment agents | SUMMIT TECHNOLOGY INC (US) | 1995-03-15 | — | — | EP | claimed |
| CN-117777759-A | Modified optically variable dye and preparation method thereof | 湖南肆玖科技有限公司 | 2024-03-29 | — | — | CN | disclosed |
| EP-3638251-B1 | BISPHOSPHOCIN GEL FORMULATIONS AND USES THEREOF | LAKEWOOD AMEDEX INC (US) | 2024-03-06 | — | — | EP | disclosed |
| CN-117396186-A | Anhydrous composition for caring for and/or making up keratin materials | 莱雅公司 | 2024-01-12 | — | — | CN | disclosed |
| WO-2001072276-A1 | NOVEL DELIVERY SYSTEM FOR INORGANIC SUNSCREENS | FINETEX, INC. (US) | 2001-10-04 | — | — | WO | disclosed |
| US-5952392-A | THERAPEUTIC TREATMENT OF VIRAL INFECTIONS AND SKIN INFLAMMATION USING A MIXTURE CONTAINING A NONIONIC SURFACTANT BLOCK POLYMER | AVANIR PHARMACEUTICALS (US) | 1999-09-14 | — | — | US | disclosed |
| US-4150970-A | 1-TRIACONTANOL | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 1979-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210361689-A1 | BISPHOSPHOCIN GEL FORMULATIONS AND USES THEREOF | BPGM, PPIP5K2, SOST | ALDH1A1 3544/4885TSHR 4193/4885LMNA 3761/4885 |
| US-20200360415-A1 | BISPHOSPHOCIN GEL FORMULATIONS AND USES THEREOF | BPGM, PPIP5K2, SOST | ALDH1A1 3544/4885TSHR 4193/4885LMNA 3761/4885 |
| US-20180353529-A1 | BISPHOSPHOCIN GEL FORMULATIONS AND USES THEREOF | BPGM, PPIP5K2, SOST | ALDH1A1 3544/4885TSHR 4193/4885LMNA 3761/4885 |
| US-20230125677-A1 | BISPHOSPHOCIN GEL FORMULATIONS AND USES THEREOF | BPGM, PPIP5K2, SOST | ALDH1A1 3544/4885TSHR 4193/4885LMNA 3761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.