Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3139430 | 0.92 | ALDH1A1 (0.42) | ALDH1A1TSHRMAPK1CYP4F2CYP4A11 | |
| SCHEMBL11416365 | 0.83 | ALDH1A1 (0.36) | ALDH1A1TSHRMEN1KMT2ATHRB | |
| SCHEMBL25302762 | 0.81 | CYP4F2 (0.43) | ALDH1A1TSHRMEN1KMT2ATHRB | |
| Methacrylic Acid SCHEMBL5382174 | 0.81 | THRB (0.32) | TSHRTHRBCYP4F2CYP4A11 | |
| Methacrylic Acid SCHEMBL1200080 | 0.81 | THRB (0.32) | TSHRTHRBCYP4F2CYP4A11 | |
| SCHEMBL8531703 | 0.78 | TSHR (0.39) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| SCHEMBL10742816 | 0.78 | CYP4F2 (0.37) | ALDH1A1TSHRCYP4F2CYP4A11 | |
| SCHEMBL7023619 | 0.75 | — | — | |
| SCHEMBL48477 | 0.75 | ALDH1A1 (0.31) | ALDH1A1TSHR | |
| SCHEMBL7961127 | 0.74 | ALDH1A1 (0.39) | ALDH1A1TSHRMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4284506-A | POLYURETHANES | NL INDUSTRIES, INC. (US) | 1981-08-18 | — | — | US | claimed |
| US-4238592-A | Method for production of duroplastic, single-component polyurethanes | CHEMISCHE WERKE HULS AG (DE) | 1980-12-09 | — | — | US | claimed |
| WO-2022004249-A1 | MULTILAYERED POLYESTER FILM | 東洋紡株式会社 | 2022-01-06 | — | — | WO | disclosed |
| CN-109071574-A | hydrophilic silane | 美国陶氏有机硅公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-109069368-A | HYDROPHILIC SILANES | 美国陶氏有机硅公司 | 2018-12-21 | — | — | CN | disclosed |
| US-8614352-B2 | Method for producing color-stable MDA and MDI | BASF SE (DE) | 2013-12-24 | — | — | US | disclosed |
| US-20120046497-A1 | METHOD FOR PRODUCING COLOR-STABLE MDA AND MDI | BASF SE (DE) | 2012-02-23 | — | — | US | disclosed |
| US-5336585-A | Free of tunnel voids | ASAHI KASEI KOGYO KABUSHIKI (JP) | 1994-08-09 | — | — | US | disclosed |
| US-5290632-A | Component A of castor oil, low molecular weight polyol and elastomer, Component B of polymeric polyisocyanate | W. R. GRACE & CO.-CONN. (US) | 1994-03-01 | — | — | US | disclosed |
| EP-0568388-A1 | Liquid coatings for cast iron | W.R. Grace & Co.-Conn. (US) | 1993-11-03 | — | — | EP | disclosed |
| US-5207942-A | Colorless | BASF AKTIENGESELLSCHAFT (DE) | 1993-05-04 | — | — | US | disclosed |
| US-5091455-A | Two-stage heating to cure a mixture of polyol, diisocyanate, polyurethane catalyst and plastisol of plasticizer and a vinyl chloride resin; seals; adhesives; automobiles | W. R. GRACE & CO.-CONN. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0344512-A2 | Liquid protective coating for concrete surfaces | W.R. Grace & Co.-Conn. (US) | 1989-12-06 | — | — | EP | disclosed |
| US-4877829-A | POLYURETHANE CONTAINING CASTOR OIL, LOW MOLECULAR WEIGHT POLYOL, ELASTOMER, DIPHENYLMETHANE DIISOCYANATE | W. R. GRACE & CO.-CONN. (US) | 1989-10-31 | — | — | US | disclosed |
| US-4855185-A | APPLYING MEMBRANE COMPOSED OF LOW MOLECULAR WEIGHT POLYOL, POLYOXYPROPYLENETRIOL, ELASTOMER REACTED WITH POLYISOCYANATE MIXTURE | W. R. GRACE & CO.-CONN. (US) | 1989-08-08 | — | — | US | disclosed |
| US-4788269-A | POLYOL MONOMER, POLYOXYPROPYLENE TRIOL, ELASTOMER, DIPHENYLMETHANE DIISOCYANATE | W. R. GRACE & CO.-CONN. (US) | 1988-11-29 | — | — | US | disclosed |
| US-4405725-A | Foamed polyisocyanurates | MOBAY CHEMICAL CORPORATION (US) | 1983-09-20 | — | — | US | disclosed |
| US-4284506-A | POLYURETHANES | NL INDUSTRIES, INC. (US) | 1981-08-18 | — | — | US | disclosed |
| US-4064087-A | WITHOUT BUFFERS, FREE RADICAL CATALYSTS, ADDITION POLYMERIZATION ON | PPG INDUSTRIES, INC. (US) | 1977-12-20 | — | — | US | disclosed |