Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6645696 | 0.85 | — | — | |
| SCHEMBL6533441 | 0.72 | SMN1; SMN2 (0.36) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL4585951 | 0.69 | — | — | |
| SCHEMBL29129485 | 0.68 | CYP4F2 (0.39) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL4587444 | 0.67 | — | — | |
| SCHEMBL4586133 | 0.65 | — | — | |
| SCHEMBL4587475 | 0.65 | — | — | |
| Methyl Alcohol SCHEMBL3866911 | 0.62 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL156683 | 0.62 | — | — | |
| 1,4-Butanediol SCHEMBL28392323 | 0.62 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927183-B1 | SPIROCYCLIC METALLOPROTEASE INHIBITORS | PROCTER & GAMBLE (US) | 2004-07-28 | — | — | EP | disclosed |
| US-6015912-A | TREATING ARTHRITIS, CANCER, CARDIOVASCULAR DISORDERS, SKIN DISORDERS, OCULAR DISORDERS, INFLAMMATION, GUM DISEASE | THE PROCTER & GAMBLE COMPANY (US) | 2000-01-18 | — | — | US | disclosed |