Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.34 |
| ▸ | PPARG | P37231 | 7/20 | 0.34 |
| ▸ | PPARD | Q03181 | 7/20 | 0.34 |
| ▸ | PPARA | Q07869 | 7/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.34 |
| ▸ | TLR2 | O60603 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | FABP4 | P15090 | 2/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL207533 | 0.76 | GPR84 (0.48) | ALDH1A1AKR1B1GPR84PPARGPPARD | |
| SCHEMBL207371 | 0.72 | AKR1B1 (0.32) | ALDH1A1AKR1B1GPR84PPARGPPARD | |
| SCHEMBL481536 | 0.65 | CETP (0.37) | ALDH1A1AKR1B1GPR84PPARGPPARD | |
| SCHEMBL23397846 | 0.65 | AKR1B1 (0.37) | ALDH1A1AKR1B1GPR84PPARGPPARD | |
| SCHEMBL30538380 | 0.65 | CETP (0.37) | ALDH1A1AKR1B1GPR84PPARGPPARD | |
| SCHEMBL3096917 | 0.63 | FFAR3 (0.41) | ALDH1A1AKR1B1TDP1 | |
| Pentane SCHEMBL9698801 | 0.63 | ALDH1A1 (0.58) | ALDH1A1AKR1B1TP53GPR84PPARG | |
| Pentane SCHEMBL7056101 | 0.63 | ALDH1A1 (0.58) | ALDH1A1AKR1B1TP53GPR84PPARG | |
| Hexane SCHEMBL5713350 | 0.63 | TSHR (0.60) | ALDH1A1AKR1B1TP53GPR84PPARG | |
| Hexane SCHEMBL10920385 | 0.63 | TSHR (0.60) | ALDH1A1AKR1B1TP53GPR84PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349539-B1 | BIOCOMPATIBLE COMPOSITE | VASCUTEK LTD (GB) | 2004-10-13 | — | — | EP | disclosed |
| US-20040115237-A1 | vascular graft comprising a composite comprising a polymer and an active ingredient such a aspirin, incorporated into composite with ultrasonication | VASCUTEK LIMITED (GB) | 2004-06-17 | — | — | US | disclosed |
| EP-1349539-A1 | BIOCOMPATIBLE COMPOSITE | Sulzer Vascutek Limited (GB) | 2003-10-08 | — | — | EP | disclosed |
| WO-2003005990-A1 | BIOCOMPATIBLE COMPOSITE | VASCUTEK LIMITED (GB) | 2003-01-23 | — | — | WO | disclosed |