Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 11/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6680801 | 0.96 | ADRB3 (0.46) | ADRB3ADRB1CYP4F2CYP4A11MEN1 | |
| SCHEMBL6677081 | 0.94 | CYP4F2 (0.42) | ADRB3ADRB1CYP4F2CYP4A11MEN1 | |
| SCHEMBL6677033 | 0.89 | ADRB3 (0.44) | ADRB3ADRB1CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL6676287 | 0.87 | ADRB3 (0.55) | ADRB3ADRB1 | |
| SCHEMBL6687818 | 0.85 | ADRB3 (0.39) | ADRB3ADRB1MEN1KMT2AMAPT | |
| SCHEMBL6679530 | 0.85 | ADORA1 (0.38) | ADRB3ADRB1KMT2AMAPTALDH1A1 | |
| SCHEMBL6682215 | 0.84 | ADRB3 (0.42) | ADRB3ADRB1 | |
| SCHEMBL6678492 | 0.84 | ALDH1A1 (0.39) | ADRB3ADRB1MAPTALDH1A1ADRB2 | |
| Hydrochloric Acid SCHEMBL6678511 | 0.83 | ADRB3 (0.57) | ADRB3ADRB1 | |
| Hydrochloric Acid SCHEMBL6678516 | 0.83 | ADRB3 (0.57) | ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004045610-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 2004-06-03 | — | — | WO | disclosed |