Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | RECQL | P46063 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3463529 | 0.87 | NPC1 (0.77) | NPC1RAB9ARECQLALDH1A1KMT2A | |
| SCHEMBL1340160 | 0.83 | NPC1 (0.74) | NPC1RAB9ARECQLALDH1A1KMT2A | |
| SCHEMBL31734218 | 0.81 | NPC1 (0.72) | NPC1RAB9ARECQLALDH1A1KMT2A | |
| SCHEMBL8581954 | 0.81 | NPC1 (0.72) | NPC1RAB9ARECQLALDH1A1KMT2A | |
| SCHEMBL29794119 | 0.81 | NPC1 (0.72) | NPC1RAB9ARECQLALDH1A1KMT2A | |
| SCHEMBL2304857 | 0.81 | NPC1 (0.72) | NPC1RAB9ARECQLALDH1A1KMT2A | |
| SCHEMBL50769 | 0.81 | NPC1 (0.72) | NPC1RAB9ARECQLALDH1A1KMT2A | |
| SCHEMBL1123538 | 0.81 | NPC1 (0.72) | NPC1RAB9ARECQLALDH1A1KMT2A | |
| SCHEMBL18012379 | 0.81 | NPC1 (0.72) | NPC1RAB9ARECQLALDH1A1KMT2A | |
| SCHEMBL30517741 | 0.81 | NPC1 (0.72) | NPC1RAB9ARECQLALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012024558-A2 | LIGHT MEDIATED REGULATION OF PROTEIN DIMERIZATION | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2012-02-23 | — | — | WO | disclosed |