SCHEMBL1123538

SCHEMBL1123538

CCCCCCOc1ccccc1[N+](=O)[O-]

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.72
RAB9A P51151 3/20 0.72
RECQL P46063 2/20 0.72
ALDH1A1 P00352 5/20 0.64
LMNA P02545 3/20 0.64
L3MBTL1 Q9Y468 2/20 0.64
KMT2A Q03164 4/20 0.60
SMN1; SMN2 Q16637 2/20 0.60
MAPT P10636 4/20 0.59
MEN1 O00255 2/20 0.59
MAPK1 P28482 1/20 0.59
KDM4E B2RXH2 1/20 0.56
TDP1 Q9NUW8 1/20 0.54
HTT P42858 3/20 0.54
CYP1A2 P05177 1/20 0.53
CYP2D6 P10635 1/20 0.53
CYP2C19 P33261 1/20 0.53
HPGD P15428 1/20 0.53
THRA P10827 1/20 0.52
THRB P10828 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8055173 1.00 NPC1 (0.72) NPC1RAB9ARECQLALDH1A1LMNA
SCHEMBL30517741 1.00 NPC1 (0.72) NPC1RAB9ARECQLALDH1A1LMNA
SCHEMBL50769 1.00 NPC1 (0.72) NPC1RAB9ARECQLALDH1A1LMNA
SCHEMBL29794119 1.00 NPC1 (0.72) NPC1RAB9ARECQLALDH1A1LMNA
SCHEMBL2304857 1.00 NPC1 (0.72) NPC1RAB9ARECQLALDH1A1LMNA
SCHEMBL18012379 1.00 NPC1 (0.72) NPC1RAB9ARECQLALDH1A1LMNA
SCHEMBL8581954 1.00 NPC1 (0.72) NPC1RAB9ARECQLALDH1A1LMNA
SCHEMBL31734218 1.00 NPC1 (0.72) NPC1RAB9ARECQLALDH1A1LMNA
SCHEMBL29361974 1.00 NPC1 (0.72) NPC1RAB9ARECQLALDH1A1LMNA
SCHEMBL3462898 1.00 NPC1 (0.72) NPC1RAB9ARECQLALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1455919-B1 IODINE EXTRACTION METHOD COMMISSARIAT ENERGIE ATOMIQUE (FR) 2011-02-09 EP claimed
US-20100224030-A1 INDIUM RECOVERY BY SUPPORTED LIQUID MEMBRANE WITH STRIP DISPERSION CHUNG YUAN CHRISTIAN UNIVERSITY (TW) 2010-09-09 US claimed
US-6433163-B1 EXTRACTION, SEPARATION COMMODORE SEPARATION TECHNOLIGIES, INC. 2002-08-13 US claimed
US-6350419-B1 SUPPORTED LIQUID MEMBRANE/ STRIP DISPERSION FOR REMOVAL OF METALS COMMODORE SEPARATION TECHNOLOGIES INC. 2002-02-26 US claimed
US-6328782-B1 TREATING FEED SOLUTION CONTAINING RADIONUCLIDES OR METALS BY PASSING FEED SOLUTION ON ONE SIDE OF SUPPORTED LIQUID MEMBRANE EMBEDDED IN MICROPOROUS SUPPORT AND REMOVING RADIONUCLIDES BY USE OF STRIP DISPERSION ON OTHER SIDE OF MEMBRANE; SEPARATION COMMODORE SEPARATION TECHNOLOGIES, INC. 2001-12-11 US claimed
US-20010029810-A1 Alkyl phenylphosphonic acid extractants and processes for their manufacture HO W S WINSTON (US) 2001-10-18 US claimed
WO-2001056933-A2 COMBINED SUPPORTED LIQUID MEMBRANE/STRIP DISPERSION PROCESSES AND EXTRACTANTS COMMODORE SEPARATION TECHNOLOGIES, INC. (US) 2001-08-09 WO claimed
US-6171563-B1 Supported liquid membrane process for chromium removal and recovery COMMODORE SEPARATION TECHNOLOGIES, INC. 2001-01-09 US claimed
WO-1998010852-A1 SUPPORTED LIQUID MEMBRANE SEPARATION COMMODORE SEPARATION TECHNOLOGIES, INC. (US) 1998-03-19 WO claimed
US-20250034139-A1 AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC, AND ANTICANCER ACTIVITY PHARMA CINQ, LLC 2025-01-30 US disclosed
US-12139483-B2 Imidazoquinolyl compounds having anti-inflammatory, antifungal, antiparasitic, and anticancer activity PHARMA CINQ, LLC (US) 2024-11-12 US disclosed
US-20210163476-A1 IMIDAZOQUINOLYL COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC, AND ANTICANCER ACTIVITY PHARMA CINQ, LLC 2021-06-03 US disclosed
US-10934284-B2 Aminoquinazoline compounds having anti-inflammatory, antifungal, antiparasitic, and anticancer activity WELLSTAT THERAPEUTICS CORPORATION (US) 2021-03-02 US disclosed
CN-108250142-B Amine compounds having anti-inflammatory, antifungal, antiparasitic and anticancer activity 维尔斯达医疗公司 2021-01-26 CN disclosed
WO-1994024138-A1 CALIX|4|ARENE CROWN ETHERS, METHOD FOR PREPARING SAME, AND USE THEREOF FOR THE SELECTIVE EXTRACTION OF CAESIUM AND ACTINIDES COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1994-10-27 WO disclosed
WO-1994012502-A1 BIS-CROWN CALIX[4]ARENES, METHOD FOR PREPARING SAME AND USE THEREOF FOR SELECTIVELY RECOVERING CESIUM AND ACTINIDES COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1994-06-09 WO disclosed
US-4975456-A For inhibiting intestinal absorption of cholesterol and increasing high density lipoprotein WARNER-LAMBERT COMPANY (US) 1990-12-04 US disclosed
US-4960950-A Formation of nitrophenyl ethers from polyols and nitroanisoles THE DOW CHEMICAL COMPANY (US) 1990-10-02 US disclosed
US-4882357-A ANTICHOLESTEROL AGENT; INCREASES HIGH DENSITY LIPOPROTEINS WARNER-LAMBERT COMPANY (US) 1989-11-21 US disclosed
EP-0335274-A2 Formation of nitrophenyl ethers from polyols and nitroanisoles THE DOW CHEMICAL COMPANY (US) 1989-10-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210163476-A1 IMIDAZOQUINOLYL COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC, AND ANTICANCER ACTIVITY NOD1, NLRP3, AADAC NPC1 2710/4885RAB9A 3162/4885RECQL 1531/4885
US-20250034139-A1 AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC, AND ANTICANCER ACTIVITY AADAC, CASP1, AAAS NPC1 1958/4885RAB9A 3836/4885RECQL 3510/4885
US-12139483-B2 Imidazoquinolyl compounds having anti-inflammatory, antifungal, antiparasitic, and anticancer activity NOD1, NLRP3, AADAC NPC1 2710/4885RAB9A 3162/4885RECQL 1531/4885
US-10934284-B2 Aminoquinazoline compounds having anti-inflammatory, antifungal, antiparasitic, and anticancer activity AAAS, AADAC, NFKBIA NPC1 3086/4885RAB9A 2731/4885RECQL 1210/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.