SCHEMBL6682017

SCHEMBL6682017

CCCCC(C)c1ccccc1CC

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYSLTR2 Q9NS75 7/20 0.41
CYSLTR1 Q9Y271 7/20 0.41
TSHR P16473 2/20 0.38
POLB P06746 2/20 0.38
CNR2 P34972 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
CA2 P00918 1/20 0.35
TAS1R3 Q7RTX0 1/20 0.35
TAS1R1 Q7RTX1 1/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP3A4 P08684 1/20 0.35
GABRA1 P14867 2/20 0.34
GABRB2 P47870 2/20 0.34
LIPG Q9Y5X9 1/20 0.34
MAPT P10636 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6682255 0.94 CYSLTR2 (0.43) CYSLTR2CYSLTR1TSHRCNR2ALDH1A1
SCHEMBL6679577 0.93 CYSLTR2 (0.46) CYSLTR2CYSLTR1ALDH1A1LIPGNPSR1
SCHEMBL9722014 0.88 TSHR (0.41) CYSLTR2CYSLTR1TSHRPOLBSMN1; SMN2
SCHEMBL6685019 0.86 TSHR (0.45) CYSLTR2CYSLTR1TSHRPOLBCNR2
Ammonia Solution, Strong SCHEMBL6647616 0.85 CYSLTR2 (0.46) CYSLTR2CYSLTR1TSHRPOLBCYP3A4
SCHEMBL2697041 0.82 TSHR (0.39) CYSLTR2CYSLTR1TSHRPOLBCNR2
SCHEMBL13226180 0.82 SLC6A4 (0.46) CYSLTR2CYSLTR1TSHRALDH1A1
SCHEMBL3481601 0.81 CYSLTR2 (0.34) CYSLTR2CYSLTR1TSHRPOLBCA2
SCHEMBL477604 0.81 CYSLTR2 (0.44) CYSLTR2CYSLTR1TSHRPOLBCNR2
SCHEMBL27658986 0.81 TSHR (0.38) CYSLTR2CYSLTR1TSHRPOLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0985649-B1 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES (JP) 2004-11-24 EP disclosed
US-6462248-B1 THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS TORAY INDUSTRIES, INC. (JP) 2002-10-08 US disclosed
EP-0985649-A2 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES, INC. (JP) 2000-03-15 EP disclosed