SCHEMBL9722014

SCHEMBL9722014

CCCC(C)c1ccccc1CC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TAS1R3 Q7RTX0 1/20 0.40
TAS1R1 Q7RTX1 1/20 0.40
CYSLTR2 Q9NS75 6/20 0.40
CYSLTR1 Q9Y271 6/20 0.40
GABRA1 P14867 2/20 0.37
GABRB2 P47870 2/20 0.37
MAPT P10636 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
POLB P06746 1/20 0.35
HTT P42858 1/20 0.35
ADRA2A P08913 1/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35
MGLL Q99685 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
SLC6A2 P23975 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6682017 0.88 CYSLTR2 (0.41) TSHRSMN1; SMN2TAS1R3TAS1R1CYSLTR2
SCHEMBL6682255 0.86 CYSLTR2 (0.43) TSHRCYSLTR2CYSLTR1NPSR1
SCHEMBL6679577 0.85 CYSLTR2 (0.46) CYSLTR2CYSLTR1NPSR1
SCHEMBL31380293 0.84 TSHR (0.48) TSHRSMN1; SMN2CYSLTR2CYSLTR1GABRA1
SCHEMBL21499442 0.84 TSHR (0.38) TSHRSMN1; SMN2TAS1R3TAS1R1CYSLTR2
SCHEMBL27658986 0.84 TSHR (0.38) TSHRSMN1; SMN2TAS1R3TAS1R1CYSLTR2
SCHEMBL3627333 0.83 TSHR (0.59) TSHRGABRA1GABRB2MAPTNPSR1
SCHEMBL6546794 0.82 ALDH1A1 (0.46) TSHRSMN1; SMN2POLBHTTCYP2D6
SCHEMBL19013294 0.81 CYSLTR2 (0.47) TSHRSMN1; SMN2TAS1R3TAS1R1CYSLTR2
SCHEMBL2697157 0.81 TSHR (0.42) TSHRSMN1; SMN2CYSLTR2CYSLTR1GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5136089-A ACYLATION OF ALKYL AROMATIC HYDROCARBONS BASF AKTIENGESELLSCHAFT (DE) 1992-08-04 US disclosed