SCHEMBL6682020

SCHEMBL6682020

CCCCC(C)CCc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
SIGMAR1 Q99720 4/20 0.47
CNR2 P34972 1/20 0.44
KCNH2 Q12809 1/20 0.43
TSHR P16473 1/20 0.43
POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6682257 0.94 SIGMAR1 (0.50) CYP1A2CYP2C9CYP2C19SIGMAR1CNR2
SCHEMBL6679579 0.92 CSNK1E (0.49) CYP1A2CYP2C9CYP2C19SIGMAR1CNR2
SCHEMBL31490485 0.92 CSNK1E (0.49) CYP1A2CYP2C9CYP2C19SIGMAR1CNR2
SCHEMBL7362511 0.92 KCNH2 (0.47) CYP1A2CYP2C9CYP2C19SIGMAR1CNR2
SCHEMBL9427262 0.88 TSHR (0.46) CYP1A2CYP2C9CYP2C19SIGMAR1TSHR
SCHEMBL4785593 0.87 TSHR (0.52) CYP1A2CYP2C9CYP2C19TSHRPOLB
SCHEMBL27952343 0.85 KCNH2 (0.53) SIGMAR1KCNH2
SCHEMBL27984757 0.85 KCNH2 (0.53) SIGMAR1KCNH2
SCHEMBL3322171 0.85 KCNH2 (0.53) SIGMAR1KCNH2
SCHEMBL9543267 0.84 SIGMAR1 (0.50) SIGMAR1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4467119-A PURIFICATION OF TRIS/1-HYDROXY-3-METHYL-6-TERT-BUTYL PHENYL/BUTANE ICI AMERICAS INC. (US) 1984-08-21 US claimed
WO-2021099569-A1 PHOTOVOLTAIC MODULE BACKSHEET COMPRISING POLYOLEFIN LAYERS DSM ADVANCED SOLAR B.V. (NL) 2021-05-27 WO disclosed
CN-111408221-A Anti-haze agent and preparation method thereof 广西精典化工新材料有限公司 2020-07-14 CN disclosed
CN-109790281-A crystalline polyester resin and flame-retardant sealing resin composition 东洋纺株式会社 2019-05-21 CN disclosed
EP-2628745-B1 Silicon-containing surface modifier, resist lower layer film-forming composition containing the same, and patterning process SHINETSU CHEMICAL CO (JP) 2015-03-25 EP disclosed
EP-0985649-B1 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES (JP) 2004-11-24 EP disclosed
US-6462248-B1 THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS TORAY INDUSTRIES, INC. (JP) 2002-10-08 US disclosed
EP-0928309-B1 PROCESS FOR PRODUCING THERMOPLASTICS BASF AG (DE) 2001-06-13 EP disclosed
EP-0985649-A2 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES, INC. (JP) 2000-03-15 EP disclosed
US-5430155-A Viricides, treatment of AIDS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1995-07-04 US disclosed
US-5294720-A Viricides THE DUPONT MERCK PHARMACEUTICAL CO. (US) 1994-03-15 US disclosed
EP-0532693-A1 1,4-DIAMINO-2,3-DIHYDROXYBUTANES THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1993-03-24 EP disclosed
US-4556695-A ADDING A CHLORINATED BICUMYL COMPOUND IN THE ABSENCE OF A FLAME RETARDANT AKZO N.V. (NL) 1985-12-03 US disclosed
EP-0131323-A1 Process for the degradation of (co)polymers of propylene AKZO N.V. (NL) 1985-01-16 EP disclosed
US-4467119-A PURIFICATION OF TRIS/1-HYDROXY-3-METHYL-6-TERT-BUTYL PHENYL/BUTANE ICI AMERICAS INC. (US) 1984-08-21 US disclosed
US-4467119-A PURIFICATION OF TRIS/1-HYDROXY-3-METHYL-6-TERT-BUTYL PHENYL/BUTANE ICI AMERICAS INC. (US) 1984-08-21 US disclosed
US-4412896-A IRRADIATION SOCIETE CHIMIQUE DES CHARBONNAGES (FR) 1983-11-01 US disclosed