Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1303526 | 0.85 | GAA (0.47) | L3MBTL1KDM4EALDH1A1MAPTLMNA | |
| SCHEMBL4220098 | 0.82 | ALDH1A1 (0.47) | L3MBTL1KDM4EALDH1A1MAPTLMNA | |
| SCHEMBL6683403 | 0.82 | ALDH1A1 (0.45) | L3MBTL1KDM4EALDH1A1LMNATDP1 | |
| SCHEMBL1303637 | 0.81 | ALDH1A1 (0.44) | L3MBTL1KDM4EALDH1A1LMNATDP1 | |
| SCHEMBL6683558 | 0.80 | ALDH1A1 (0.45) | L3MBTL1KDM4EALDH1A1MAPTLMNA | |
| SCHEMBL1302718 | 0.77 | ALDH1A1 (0.45) | L3MBTL1KDM4EALDH1A1MAPTLMNA | |
| SCHEMBL6643777 | 0.77 | ALDH1A1 (0.41) | L3MBTL1KDM4EALDH1A1MAPTGAA | |
| SCHEMBL1302652 | 0.77 | ALDH1A1 (0.40) | L3MBTL1KDM4EALDH1A1MAPTTDP1 | |
| SCHEMBL6684938 | 0.77 | ALDH1A1 (0.40) | L3MBTL1KDM4EALDH1A1MAPTTDP1 | |
| SCHEMBL6643773 | 0.75 | ALDH1A1 (0.45) | L3MBTL1KDM4EALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004062661-A1 | 2-‘5-(5-CARBAMIMIDOYL-1H-HETEROARYL)-6-HYDROXYBIPHENYL-3-YL!- CARBOXYLIC ACID DERIVATIVES AS FACTOR VIIA INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2004-07-29 | — | — | WO | disclosed |