Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | POLA1 | P09884 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6684918 | 0.87 | NR3C1 (0.38) | EGLN1NR3C1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6200835 | 0.87 | NR3C1 (0.33) | EGLN1NR3C1LMNASMN1; SMN2CNR2 | |
| SCHEMBL6200529 | 0.86 | NR3C1 (0.33) | EGLN1NR3C1LMNASMN1; SMN2CNR2 | |
| SCHEMBL6196660 | 0.85 | NR3C1 (0.42) | EGLN1NR3C1LMNASMN1; SMN2CNR2 | |
| SCHEMBL6200831 | 0.85 | NR3C1 (0.33) | EGLN1NR3C1 | |
| SCHEMBL6682851 | 0.84 | EGLN1 (0.38) | EGLN1NR3C1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL6199593 | 0.82 | EGLN1 (0.39) | EGLN1NR3C1LMNASMN1; SMN2CNR2 | |
| SCHEMBL6199909 | 0.82 | EGLN1 (0.43) | EGLN1NR3C1LMNACNR2GSK3B | |
| SCHEMBL6197241 | 0.82 | EGLN1 (0.43) | EGLN1NR3C1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL6200031 | 0.81 | MEN1 (0.41) | EGLN1NR3C1ALDH1A1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004019932-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | claimed |
| WO-2004019932-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | disclosed |