Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.36 |
| ▸ | PDE5A | O76074 | 2/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 7/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6682167 | 0.87 | EGLN1 (0.37) | NR3C1EGLN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6199424 | 0.87 | EGLN1 (0.35) | NR3C1EGLN1PDE5APDPK1SMN1; SMN2 | |
| SCHEMBL6198743 | 0.86 | EGLN1 (0.35) | NR3C1EGLN1PDE5APDPK1SMN1; SMN2 | |
| SCHEMBL6199416 | 0.84 | EGLN1 (0.34) | NR3C1EGLN1PDE5APDPK1 | |
| SCHEMBL6682523 | 0.84 | EGLN1 (0.38) | NR3C1EGLN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6197455 | 0.81 | NR3C1 (0.44) | NR3C1EGLN1PDE5APDPK1 | |
| SCHEMBL6202848 | 0.80 | EGLN1 (0.36) | NR3C1EGLN1PDE5APDPK1SMN1; SMN2 | |
| SCHEMBL6216695 | 0.78 | EGLN1 (0.43) | NR3C1EGLN1PDE5ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6200203 | 0.77 | NR3C1 (0.42) | NR3C1EGLN1PDE5APDPK1SMN1; SMN2 | |
| SCHEMBL6686369 | 0.77 | MEN1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004019932-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | claimed |
| WO-2004019932-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | disclosed |